Background: Historically, tertiary syphilis infection has been the most common cause of thoracic aortic aneurysm, resulting in 5% to 10% of cardiovascular deaths until the era of antibiotics.
Methods: A 49-year-old Caucasian man presented to our institution with progressive dysphagia, weight loss, incomplete bladder emptying, alcohol and tobacco consumption, systemic arterial hypertension, Argyll Robertson pupil, leg paresthesias, and mediastinal widening. He was admitted to investigate clinical alterations. Thoracic computed tomography revealed an aortic aneurysm complicated with chronic aortic dissection from the ascending aorta to the iliac vessels with 2 communicating lumens. Cerebrospinal fluid examination tested positive for neurosyphilis in a venereal disease research laboratory test (titre 1/32).
Results: Chronic syphilitic aortic aneurysm complicated with chronic aortic dissection was diagnosed.
Conclusions: This is a unique presentation of a syphilitic infection. Syphilitic aortitis, the hallmark of cardiovascular syphilis, has become rare and is hardly considered by today's clinicians in their differential diagnosis.
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http://dx.doi.org/10.1016/j.amjsurg.2010.02.017 | DOI Listing |
J Biochem Mol Toxicol
January 2025
Department of Cardiothoracic Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou City, Hubei Province, China.
Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease (CVD) that is partly attributable to endothelial dysfunction, inflammatory response, and angiogenesis. G protein-coupled receptor 4 (GPR4), a proton-sensitive G protein-coupled receptor that is abundantly expressed in vascular endothelial cells, has been associated with numerous physiological functions. Nevertheless, its potential involvement in the development of AAA remains unexplored.
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
January 2025
Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, Japan.
Cervical aortic arch (CAA) is a rare malformation. Herein, we report a 58-year-old female patient diagnosed with left CAA with descending aortic aneurysm. Initially, the descending aorta replacement was planned via left rib-cross thoracotomy.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Vascular Surgery, Zhangzhou Affiliated Hospital of FuJian Medical University, Zhangzhou, Fujian Province, 363000, China.
Background: Thoracic aortic endovascular repair (TEVAR) is the most commonly employed method for treating type B aortic dissection (TBAD). One of the primary challenges in TEVAR is the reconstruction of the left subclavian artery (LSA). Various revascularization strategies have been utilized, including branch stent techniques, fenestration techniques, chimney techniques, and hybrid techniques.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
January 2025
Department of Surgical and Integrated Diagnostic Sciences, University of Genoa, Genoa, Italy; Clinic of Vascular and Endovascular Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Eur J Vasc Endovasc Surg
January 2025
Department of Vascular Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Objective: Inflammation seems to be crucial in the pathogenesis of abdominal aortic aneurysm (AAA). Previous research links inflammatory biomarkers, such as high sensitivity C-reactive protein (HS-CRP), to AAA. Few studies, however, have used a prospective design.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!