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Effects of an Inclusive Group-Based Naturalistic Developmental Behavioral Intervention on Active Engagement in Young Autistic Children: A Preliminary Study.
J Speech Lang Hear Res
January 2025
Center for Autism Services, Science and Innovation, Kennedy Krieger Institute, Baltimore, MD.
Purpose: Despite group-level improvements in active engagement and related outcomes, significant individual variability in response to early intervention exists. The purpose of this preliminary study was to examine the effects of a group-based Naturalistic Developmental Behavioral Intervention (NDBI) on active engagement among a heterogeneous sample of young autistic children in a clinical setting.
Method: Sixty-three autistic children aged 24-60 months ( = 44.
Impact of the COVID-19 pandemic on the incidence of occupational accidents among beneficiaries of the Unified Health System in Brazil: an interrupted time series study.
Cien Saude Colet
January 2025
Faculdade de Saúde Pública, Universidade de São Paulo (USP). Av. Dr. Arnaldo 715, Cerqueira César. 01246-904 São Paulo SP Brasil.
The scope of this study was to analyze the impact of the COVID-19 pandemic on the incidence of occupational accidents among beneficiaries of the Unified Health System in Brazil. It was an interrupted time series study, using data on occupational accidents registered by the Unified Health System from 2015 to 2020. The analysis used the Prais-Winsten generalized linear regression model.
View Article and Find Full Text PDFTemporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023.
Epidemiol Serv Saude
January 2025
Universidade Federal de São Paulo, Departamento de Enfermagem na Saúde da Mulher, São Paulo, SP, Brasil.
Objective: To analyze trends of syphilis during pregnancy and congenital syphilis, based on reported cases in São Paulo, Brazil, from 2011 to 2023.
Methods: Ecological time series study, based on data from Notifiable Health Conditions Information System records. The Prais-Winsten method was used to verify trends.
Short-term orthokeratology effects on corneal biomechanics with a focus on SPA1 and stress-strain index (SSI) parameters in pediatric myopia.
Arq Bras Oftalmol
January 2025
Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences. No. 106 Zhongshan Er Road, Guangzhou 510080, China.
Purpose: Although the orthokeratology effects on corneal biomechanics have been proven with clinical trials, reports of stiffness parameter change are scarce. This study investigated the short-term orthokeratology effects in pediatric myopia and compared stiffness parameter changes to those published in recent clinical investigations. This prospective study aimed to investigate corneal biomechanics changes induced by short-term overnight orthokeratology treatment, focusing on stiffness parameter at A1 and stress-strain index.
View Article and Find Full Text PDFRecalibrating Protection Factors Using Millisecond Hydrogen/Deuterium Exchange Mass Spectrometry.
Anal Chem
January 2025
School of Molecular and Cellular Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U.K.
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a powerful technique to interrogate protein structure and dynamics. With the ability to study almost any protein without a size limit, including intrinsically disordered ones, HDX-MS has shown fast growing importance as a complement to structural elucidation techniques. Current experiments compare two or more related conditions (sequences, interaction partners, excipients, conformational states, etc.
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