AI Article Synopsis
- Previous studies indicate that high-intensity sweeteners can lead to weight gain in rats, prompting further research into the effects of caffeine on sweetener consumption and weight gain.
- In two experiments, rats consuming caffeine-sweetened solutions showed higher intake regardless of their diet (low-fat or high-calorie), but only the low-fat diet saw a reversal in the weight gain typically associated with saccharin.
- The results highlight how caffeine influences sweetener intake and weight gain, revealing that the type of diet plays a critical role in this relationship.
Article Abstract
Previous studies show that high-intensity sweeteners can stimulate weight gain in rats. The present studies examined whether caffeine, a stimulant commonly added to beverages consumed by humans, influences intake of saccharin- or glucose-sweetened solutions or body weight gain in rats and whether the nature of the maintenance diet influences the effects of caffeine. In two experiments, rats received glucose or saccharin solution mixed with 0.125 mg/g caffeine or no caffeine. Rats consumed significantly more caffeinated than noncaffeinated solutions when they were maintained on a low-fat chow diet (Experiment 1) and when maintained on a sweet, high-fat, high calorie chow diet (Experiment 2). Consumption of saccharin resulted in higher body weight gain in both experiments. Caffeine reversed this effect in Experiment 1 (low-fat diet) but not Experiment 2 (sweet, high-fat diet). The findings extend what is known about the conditions under which consumption of high intensity sweeteners promote energy dysregulation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997566 | PMC |
| http://dx.doi.org/10.1016/j.appet.2010.08.021 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!