Synthesis and antifungal activity of benzofuran-5-ols.

Bioorg Med Chem Lett

College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea.

Published: November 2010

Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.

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http://dx.doi.org/10.1016/j.bmcl.2010.08.129DOI Listing

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