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Potential Sampling Errors in Stability Studies Due to Dead Volume in Closed System Transfer Devices.
J Pharm Technol
December 2024
Medical Laboratory, CHU UCL NAMUR, Yvoir, Belgium.
Background: Closed system transfer devices (CSTD) help to reduce the exposure of healthcare professionals to hazardous drugs. They may be used in stability studies conducted on anticancer drugs. During a stability study about polyolefin bags of gemcitabine, Tevadaptor® device was suspected of causing a bias in the evaluation of the concentrations of the first aliquots extracted from the bags.
View Article and Find Full Text PDFA Novel Combined Approach to Better Predict Sealing Performance of Luer Lock Connectivity.
PDA J Pharm Sci Technol
August 2024
BD (Becton, Dickinson and Co).
Luer systems, for example Luer-needle hub with syringe's Luer cone tip and its Luer lock Adapter, are common interface on medical devices. One of the key questions in this application is about the safety guaranty and dose accuracy. It is then crucial to study the sealing between these elements.
View Article and Find Full Text PDFNovel Thermoreversible Reverse-Phase-Shift Foam With Deployment System for Treatment of Penetrating Globe Trauma in a Newly Described Porcine Model.
Mil Med
August 2024
Benchmark Biotech LLC, Portland, OR 97206, USA.
Introduction: The initial management of penetrating ocular injuries is a major sight-threatening problem for both civilian and military medicine. A novel device (Eye-Aid) temporarily tamponades leakage from such injuries while being easy to remove upon arrival to specialized ophthalmologic care. Eye-Aid consists of a protective eye shield with an adhesive backing that connects to a portable canister containing rapidly deployable thermoresponsive foam.
View Article and Find Full Text PDFSecuring the oral and enteral oncopediatric chemotherapy process in pediatric oncology: Introduction of the ENFit™ standard in a controlled-atmosphere area and implementation of a dispensing service of medications to outpatients circuit with advice on proper use.
J Oncol Pharm Pract
April 2024
Pôle Produits de Santé, service de Pharmacie, Centre Oscar Lambret, Lille, France.
Introduction: Oral chemotherapies pediatrics are manufactured from injectable specialties in a controlled-atmosphere area. Packaged in Luer-Lock syringes, the transition to an ENFit™ connector became crucial to enable administration in surveyed patients. In parallel, a study was carried out to optimize and secure patient care by setting up a retrocession circuit.
View Article and Find Full Text PDFDevices for securing and administering pediatric compounded oral liquids: survey results from French university hospitals.
Eur J Pediatr
June 2024
Department of Pharmacy, CHU Rouen, Normandie University, UNIROUEN, U1234, F-76000, Rouen, France.
Oral liquid forms, either commercial or compounded, are preferred in pediatrics due to their suitability for weight-based dosing and acceptability for children. The choice of dosing delivery devices associated with oral liquid forms is important to ensure accurate dosing, ease of administration, and patient safety. Given the prevalence of compounding in pediatric settings, this study aimed to investigate the practices among French university hospitals concerning the selection of dosing delivery devices associated with compounding oral liquid forms for children.
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