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Associations between health, productive performance and oral fluid biomarkers in commercial pig farms.
Porcine Health Manag
December 2024
Pig Development Department, Animal and Grassland Research and Innovation Centre, Teagasc Moorepark, P61C996, Fermoy, Co. Cork, Ireland.
Background: Oral fluid contains analytes that may be reflective of health and welfare in pig herds. Additionally, oral fluid collection is a more convenient and cost-effective option when compared to blood sampling, increasing the potential of oral fluid as a non-invasive alternative tool. While a growing number of biomarkers can be measured in porcine oral fluid, the use of these analytes to compare commercial herds in veterinary practice is still limited.
View Article and Find Full Text PDFGRADE-based procalcitonin guideline for emergency departments.
Am J Emerg Med
December 2024
Department of Medicine, Division of General Internal and Emergency Medicine, Aarau, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland. Electronic address:
Procalcitonin is a useful biomarker for infection. Over the past two decades, there has been much research on the clinical applications of procalcitonin, yet the majority of these studies have been conducted in the intensive care setting. Despite the extensive use of procalcitonin in emergency departments, there have been no guidelines focusing specifically on these clinical settings.
View Article and Find Full Text PDFImmature granulocytes as an early clinical predictor in children with respiratory syncytial virus bronchiolitis.
Pediatr Int
December 2024
Department of Pediatrics, Bursa Faculty of Medicine, City Training and Research Hospital, University of Health Sciences, Bursa, Turkey.
Background: Immature granulocytes can be measured easily in a complete blood count by new automated hemolytic analyzers and have recently been studied as bio-markers in many infectious/inflammatory diseases. This study aims to investigate whether immature granulocyte percentage (IG%) would enable greater discrimination than conventionally utilized laboratory values in terms of early clinical prediction in instances with respiratory syncytial virus (RSV) bronchiolitis.
Methods: A prospective observational cohort study involved 149 individuals with RSV bronchiolitis.
Clinical and Analytical Performance Evaluation of an Automated Procalcitonin Assay.
J Appl Lab Med
December 2024
Department of Clinical Affairs, QuidelOrtho Corporation, Raritan, NJ, United States.
Article Synopsis
- The study assessed the effectiveness of the Vitros® PCT assay in evaluating procalcitonin (PCT) levels for guiding antibiotic therapy and assessing risk in patients with lower respiratory infections or sepsis.
- Results showed that Vitros PCT closely matched the KRYPTOR PCT assay, with a high correlation and precision, indicating reliable performance for clinical decision-making regarding sepsis.
- Findings suggested that changes in PCT levels over the first four days could predict 28-day mortality rates in patients with severe sepsis, highlighting the assay's value in clinical risk assessment.
Evaluating the Diagnostic and Prognostic Value of Interleukin-6 (IL-6) and Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) in Systemic Inflammatory Response Syndrome (SIRS) and Sepsis in Adults.
Cureus
November 2024
Department of Medicine, Tbilisi State Medical University, Tbilisi, GEO.
Introduction: Sepsis and systemic inflammatory response syndrome (SIRS) are significant concerns in intensive care units and contribute significantly to patient mortality. Traditional diagnostic markers such as C-reactive protein (CRP) and procalcitonin (PCT) often lack the sensitivity and specificity needed for early diagnosis and prognosis. Consequently, more reliable biomarkers are needed.
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