The management protocol for differentiated thyroid cancer includes whole body iodine-131 imaging, to detect residual thyroid tissue and distant metastasis, after thyroidectomy. However, the diagnostic dose of radioiodine may fail to detect the non-functioning or poorly functioning metastasis. We present a case where hybrid single photon-emission computed tomographic and computed tomographic (SPECT-CT) fusion imaging, using a diagnostic dose of iodine-131, was able to detect both functioning as well as non-functioning pulmonary metastases, prior to high-dose radioiodine therapy.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934597 | PMC |
| http://dx.doi.org/10.4103/0972-3919.63599 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
First-in-human SPECT/CT imaging of [At]PSMA-5: targeted alpha therapy in a patient with refractory prostate cancer.
Eur J Nucl Med Mol Imaging
December 2024
Department of Radiology, Graduate School of Medicine, Osaka University, Suita, Japan.
Analysis of the application value of SUV in quantitative SPECT/CT for diagnosing benign and malignant bone lesions.
Hell J Nucl Med
December 2024
Department of Obstetrics and Gynecology, Shiyan Matenal and Child Health Hospital, Shiyan, Hubei, China.
Objective: To analyze the application value of standardized uptake value (SUV) in quantitative single-photon emission computed tomography/computed tomography (SPECT/CT) based on the maximum expectation reconstruction algorithm for diagnosing benign and malignant bone lesions.
Subjects And Methods: A retrospective analysis was conducted on the clinical data of 83 patients suspected of bone metastasis who underwent quantitative SPECT/CT bone scans in our hospital from September 2023 to July 2024. A total of 91 high-metabolic bone lesions were outlined for SUV measurement, while the spinal SUV of patients with normal bone metabolism were outlined as the control group (46 vertebral bodies).
HER2-Targeted Affibody Molecule 99mTc-ABH2 for Imaging HER2 Expression in Breast Cancer.
Clin Nucl Med
January 2025
From the Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Purpose: Accuracy in in vivo assessment of human epidermal growth factor receptor type 2 (HER2) status is crucial for predicting the response to HER2-targeted therapies in breast cancer. This study assessed the safety, feasibility, and diagnostic accuracy of 99mTc-ABH2, a reengineered affibody molecule with radionuclide labeling, for HER2 expression in breast cancer using SPECT/CT imaging, compared with 18F-FDG PET/CT.
Patients And Methods: Thirty-six patients suspected of primary breast cancer were enrolled in this prospective, single-center study from March to July in 2023.
Classification of Artifacts in Multimodal Fused Images using Transfer Learning with Convolutional Neural Networks.
Curr Med Imaging
November 2024
Department of Biomedical Engineering, Vignan's Foundation for Science, Technology, and Research, Guntur, Andhra Pradesh, 522213, India.
Introduction: Multimodal medical image fusion techniques play an important role in clinical diagnosis and treatment planning. The process of combining multimodal images involves several challenges depending on the type of modality, transformation techniques, and mapping of structural and metabolic information.
Methods: Artifacts can form during data acquisition, such as minor movement of patients, or data pre-processing, registration, and normalization.
Optimal DaTQUANT Thresholds for Diagnostic Accuracy of Dementia with Lewy Bodies (DLB) and Parkinson's Disease (PD).
Tomography
October 2024
Statistics Consulting Laboratory, BIO5 Institute, University of Arizona, Tucson, AZ 85719, USA.
Quantitative thresholds are helpful to define an abnormal DaT SPECT in patients with suspected nigrostriatal degenerative diseases (NSDD). The optimal DaTQUANT threshold for diagnostic accuracy of DaT SPECT across combined movement and cognitive disorder populations has been previously described. : We established optimal DaTQUANT thresholds that enhance the discrimination between dementia with Lewy bodies (DLB) and non-DLB dementia types, as well as between Parkinsonian syndromes (PS) and conditions not characterized by nigrostriatal degeneration (non-PS).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!