Examination of 15 patients with clofelin poisoning cleared up clinical symptoms of the condition. The impairment was chiefly inflicted to cardiovascular system and neuropsychic status. There appeared arterial hypotonia, long-term orthostatic hypotonia combined with bradycardia and extrasystolic arrhythmia. Early hours of poisoning can be accompanied with high pressure (hypertensive phase). ECG records sinus bradycardia and early ventricular repolarization. Neuropsychic alterations involve drowsiness, stupor++, psychic inhibition, visual and auditory hallucinations, photopsia. The condition was managed symptomatically. All the patients recovered.
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J Med Internet Res
January 2025
Institute for Entrepreneurship, Technology Management and Innovation (EnTechnon), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Background: Digital health technology (DHT) has the potential to revolutionize the health care industry by reducing costs and improving the quality of care in a sector that faces significant challenges. However, the health care industry is complex, involving numerous stakeholders, and subject to extensive regulation. Within the European Union, medical device regulations impose stringent requirements on various ventures.
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January 2025
Department of Health Promotion and Health Education, College of Education, National Taiwan Normal University, Taipei, Taiwan.
Background: Chronic kidney disease (CKD) imposes a significant global health and economic burden, impacting millions globally. Despite its high prevalence, public awareness and understanding of CKD remain limited, leading to delayed diagnosis and suboptimal management. Traditional patient education methods, such as 1-on-1 verbal instruction or printed brochures, are often insufficient, especially considering the shortage of nursing staff.
View Article and Find Full Text PDFPLoS One
January 2025
Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.
Introduction: 22q11 deletion syndrome (22q11DS) results from a microdeletion on chromosome 22 and is the most common microdeletion disorder in humans, affecting 1 in 2148 live births. Clinical manifestations vary widely among individuals and across different life stages. Effective management requires the involvement of a specialized multidisciplinary team.
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January 2025
Department of Emergency Medicine, Division of Pediatric Emergency Medicine, Mayo Clinic, Rochester, MN.
Objectives: ImPACTS (Improving Acute Care Through Simulation) is a collaborative simulation-based program partnering pediatric specialty centers ("hubs") with general emergency departments (GEDs) to improve pediatric acute care. Objective measurements of ImPACTS, such as evaluating Pediatric Readiness Score (PRS) and simulation-based outcome improvements, have been reported previously. Barriers to and facilitators of program involvement and the downstream effects of the program have not been previously described.
View Article and Find Full Text PDFInfect Dis (Lond)
January 2025
Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Purpose: Infective endocarditis (IE) is diagnosed using the Duke criteria, which were updated in 2023. In the Duke-ISCVID 2023 criteria, was recognised as a typical IE pathogen. This study investigates the impact of this change and compares the clinical characteristics of IE to IE caused by other pathogens.
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