AI Article Synopsis
- The incidence of unknown primary head and neck tumors with metastatic cervical lymph nodes ranges from 2% to 9%.
- A case study of a 75-year-old woman showed her only symptom was unilateral lymphadenopathy, with initial exams failing to identify the primary tumor.
- F-18 FDG PET/CT imaging successfully located a small tumor in the uvula, confirming it as the source of her metastatic squamous cell carcinoma.
Article Abstract
Incidence of unknown primary head/neck tumors with metastatic cervical lymphadenopathy at time of diagnosis is approximately 2% to 9%. Detecting site of original disease is challenging. We present a 75-year-old woman with bulky unilateral level 2 and 3 lymphadenopathy. Clinical examination and computed tomography (CT) did not reveal detectable abnormalities except neck-node metastases; biopsy indicated metastatic squamous cell carcinoma (SCC). F-18 FDG PET/CT imaging was performed to detect the primary tumor site, which revealed a small metabolically-avid lesion in uvula, biopsy demonstrated SCC, the origin of metastatic disease. F-18 FDG PET/CT imaging of unknown primary head/neck tumors can have positive impact in identifying small occult primary tumor foci.
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| http://dx.doi.org/10.1097/RLU.0b013e3181ef09cb | DOI Listing |
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