In the present study six probiotic Lactobacillus rhamnosus strains were investigated for their ability to survive in the human upper gastrointestinal tract through a dynamic gastric model of digestion. MRS broth was used as delivery vehicle and survival was investigated during in vitro gastric and gastric plus duodenal digestion. Results highlighted that all tested strains showed good survival rate during both gastric and duodenal digestion. In particular, three strains exhibited a great survival showing a recovery percentage in the range between 117 and 276%. In agreement with survival data, high lactic acid production was detected for all strains, confirming their metabolic activity during digestion.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fm.2010.07.019DOI Listing

Publication Analysis

Top Keywords

lactobacillus rhamnosus
8
rhamnosus strains
8
upper gastrointestinal
8
gastrointestinal tract
8
gastric duodenal
8
duodenal digestion
8
survival
5
strains
5
survival lactobacillus
4
strains upper
4

Similar Publications

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease often treated with glucocorticoids, which can lead to complications such as osteoporosis and an increased infection risk. Hence, identifying safe and effective treatment strategies is crucial. has shown promise in improving immune disorders.

View Article and Find Full Text PDF

Integrative Omics and Gene Knockout Analyses Suggest a Possible Gossypol Detoxification Mechanism and Potential Key Regulatory Genes of a Ruminal Strain.

J Agric Food Chem

January 2025

State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Gossypol removal is crucial for the resourceful utilization of cottonseed meals in the food and feed industries. Herein, we investigated the comprehensive detoxification mechanism of a gossypol-tolerant strain of (WK331) newly isolated from the rumen. Biodegradation assays showed that WK331 removes over 80% of free gossypol, of which 50% was biodegraded and 30% was converted into bound gossypol.

View Article and Find Full Text PDF

Influence of the addition of gum arabic and xanthan gum in the preparation of sodium alginate microcapsules coated with chitosan hydrochloride on the survival of Lacticaseibacillus rhamnosus GG.

Int J Biol Macromol

December 2024

Federal University of Pernambuco (UFPE), Av. Profª Morais Rego, 1235, University City, 50670-901 Recife, Brazil; Keizo Asami Institute (iLIKA), Av. Prof. Morais Rego, 1235, University City, 50670-901 Recife, Brazil. Electronic address:

The microencapsulation of Lactocaseibacillus rhamnosus GG in a matrix of sodium alginate, xanthan gum, gum arabic and chitosan hydrochloride is a promising strategy for protecting this probiotic during passage through the gastrointestinal tract. This study evaluated the influence on the viability of Lactocaseibacillus rhamnosus GG encapsulated with these polymers by external ionic gelation with vibratory extrusion and the microcapsules that showed the best results of capsulation efficiency, viability, size and morphology were analyzed by Fourier transform infrared spectroscopy (FTIR), thermal analysis (TGA) and exposure to environmental stress conditions and gastrointestinal simulation. The result revealed encapsulation efficiency values above 95 % for all formulations and survival rate higher than 6 log CFU/mL for most analyzed groups.

View Article and Find Full Text PDF

Introduction: Consuming hypercaloric diets during pregnancy induces metabolic, immune, and maternal intestinal dysbiosis disorders. These conditions are transferred to the offspring through the placenta and breastfeeding, increasing susceptibility to metabolic diseases. We investigated the effect of GG supplementation on offspring maternally programmed with a hypercaloric diet.

View Article and Find Full Text PDF

Background: Antiretroviral therapy (ART) causes osteoporosis and bone fractures, increasing morbidity and mortality in people living with HIV (PLH). ART induces immune reconstitution bone loss (IRBL), an inflammatory reaction associated with immune system reactivation. Women represent >50% of PLH, and many are now undergoing menopause, a major cause of postmenopausal osteoporosis that also increases fracture risk.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!