Background: Many medical laboratory tests can now be done near the patient (point-of-care testing, POCT), ranging from basic blood glucose measurement to complex coagulation testing. Switching from conventional laboratory testing to POCT shortens the time to decision-making about further testing or treatment, as delays are no longer caused by specimen transport and preparation, and the test results are rapidly available at the point of care. Better medical outcomes and lower costs may ensue.
Method: Selective literature review.
Results: The available methods and equipment enable persons not specially trained in laboratory medicine to perform high-quality laboratory testing at the point of care, under certain conditions. Before POCT is introduced in a hospital or outpatient practice, a cost-benefit analysis should be performed, because the introduction is costly and requires a certain amount of organizational work especially for quality management. The potential medical and economic benefits should be assessed individually in each case.
Conclusion: POCT for certain applications is a useful complement to conventional laboratory testing. The future utilization of POCT will depend not only on technical advances, but also on developments in costs and reimbursement.
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http://dx.doi.org/10.3238/arztebl.2010.0561 | DOI Listing |
Int J Biol Macromol
January 2025
Iranian Research Organization for Science and Technology (IROST), Sh. Ehsani Rad St., Enqelab St., Ahmadabad Mostoufi Rd., Azadegan Highway, P. O. Box 33535-111, Tehran 3313193685, Iran.
Bacterial cellulose, with mechanical strength, high water absorption, and crystallinity, is used in eco-friendly packaging, wound dressings, and drug delivery systems. Despite its potential, industrial-scale production is limited by inefficiency and high costs, requiring high-yield strains and optimized growth conditions. This study found that indigenous isolates produce superior bacterial cellulose compared to standard strains.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background And Objective: To determine whether there is disproportionate reporting of hepatobiliary disorders in the United States (US) FDA Adverse Event Reporting System (FAERS) for individuals prescribed ketamine or esketamine.
Design: We identified Medical Dictionary for Regulatory Activities (MedDRA) terms in the FAERS related to hepatobiliary disorders.
Main Measures: Formulations of ketamine and esketamine were evaluated for the proportionality of reporting for each hepatobiliary disorder parameter using the reporting odds ratio (ROR).
Comp Biochem Physiol C Toxicol Pharmacol
January 2025
Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China. Electronic address:
The small abalone (Haliotis diversicolor) is an economic shellfish cultured in the south coast of China. In recent years, the frequent occurrence of the disease has led to significant mortality in abalone farms. Deleted in malignant brain tumors 1 (DMBT1), a member of the scavenger receptor cysteine-rich (SRCR) protein family, plays an important role in host defense.
View Article and Find Full Text PDFCurr Biol
January 2025
Max Planck Institute for Biological Intelligence, 82152 Martinsried, Germany. Electronic address:
Brood care relies on interactions between parents and offspring. Emergence of nestlings from their nest has been hypothesized to rely on the readout by the parent of the maturational state of the young. Theoretical considerations predict a conflict: parents should push for early emergence, if possible, to reduce care demands and maximize the number of reproductive cycles, whereas offspring should delay leaving to maximize resource allocation and protection by the parents.
View Article and Find Full Text PDFDiagn Microbiol Infect Dis
December 2024
Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia.
Background: Quality assurance programs (QAPs) are used to evaluate the analytical quality of a diagnostic test and provide feedback to improve quality processes in testing. Rapid diagnostic tests were used in both laboratory and non-laboratory settings to diagnose COVID-19, although varied in reported performance. We aimed to design and implement a QAP for antigen rapid diagnostic tests (Ag-RDTs) for COVID-19 in Cambodia, Lao PDR, and Papua New Guinea.
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