A new approach to the discovery of cancer therapeutics is emerging that begins with the cancer patient. Genomic analysis of primary tumors is providing an unprecedented molecular characterization of the disease. The next step requires relating the genetic features of cancers to acquired gene and pathway dependencies and identifying small-molecule therapeutics that target them.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939009 | PMC |
| http://dx.doi.org/10.1038/nbt0910-904 | DOI Listing |
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