Background: It has been suggested that the instillation of 2 M hydrochloric acid (HCl) can clear bacterial and fungal colonization in central venous catheters (CVCs). The aim of the study was to determine the physical effect of HCl on the inner surface of silicone rubber Hickman CVCs.
Methods: Five CVCs had 2 M HCl installed and 5 CVCs had saline installed for 30 minutes once a week for 12 weeks. Before instillation and after infusion, a section of each CVC was removed and examined by scanning electron microscopy. The examination was blinded.
Result: Over 12 weeks no damage was detected in the CVCs. There was no difference between the CVCs flushed with saline compared with those flushed with HCl.
Conclusions: Repetitive instillation of 2 M HCL in CVCs did not cause electron microscopically detectable damage of the silicone rubber CVCs.
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