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Trophic modulation of endophytes by rhizosphere protists.
ISME J
January 2024
Institute of Science and Technology, Niigata University, Nishi-ku, Niigata 950-2181, Japan.
Article Synopsis
- The study investigates how predatory protists affect the composition of endophytic bacteria in plants by examining interactions in the rhizosphere, the soil region around plant roots.
- Experiments were conducted using three different protist species across various soil types to observe how these predators influence the microbial community dynamics, revealing unpredictable chaotic patterns instead of consistent outcomes.
- The findings suggest that protists play a significant role in shaping root-endophyte communities, which could provide insights for improving plant health and crop production through better understanding of these interactions.
Deciphering the molecular heterogeneity of intermediate- and (very-)high-risk non-muscle-invasive bladder cancer using multi-layered studies.
Front Oncol
October 2024
Department of Urology, University Hospitals Leuven, Leuven, Belgium.
Bladder cancer (BC) is the most common malignancy of the urinary tract. About 75% of all BC patients present with non-muscle-invasive BC (NMIBC), of which up to 70% will recur, and 15% will progress in stage and grade. As the recurrence and progression rates of NMIBC are strongly associated with some clinical and pathological factors, several risk stratification models have been developed to individually predict the short- and long-term risks of disease recurrence and progression.
View Article and Find Full Text PDFOn the Roles of Protein Intrinsic Disorder in the Origin of Life and Evolution.
Life (Basel)
October 2024
Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.
Obviously, the discussion of different factors that could have contributed to the origin of life and evolution is clear speculation, since there is no way of checking the validity of most of the related hypotheses in practice, as the corresponding events not only already happened, but took place in a very distant past. However, there are a few undisputable facts that are present at the moment, such as the existence of a wide variety of living forms and the abundant presence of intrinsically disordered proteins (IDPs) or hybrid proteins containing ordered domains and intrinsically disordered regions (IDRs) in all living forms. Since it seems that the currently existing living forms originated from a common ancestor, their variety is a result of evolution.
View Article and Find Full Text PDFVaginal host response to polycarbonate urethane, an alternative material for the repair of pelvic organ prolapse.
Acta Biomater
November 2024
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; Magee-Womens Research Institute, Pittsburgh, PA, United States; Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, United States.
Complications following surgical repair of pelvic organ prolapse (POP) with polypropylene mesh (PPM) are common. Recent data attributes complications, in part, to stiffness mismatches between the vagina and PPM. We developed a 3D printed elastomeric membrane (EM) from a softer polymer, polycarbonate urethane (PCU).
View Article and Find Full Text PDFEnigmatic thymus: Variations in anatomical localisation of thymic tissue as an easily misdiagnosed congenital anomaly in surgical practice.
World J Clin Cases
September 2024
Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, Bratislava 81372, Slovakia.
We point out the issue of differential diagnosis regarding the finding of ectopically localised thymic tissue (a thymic cyst) in the neck. Thymic tissue can be found anywhere along its developmental tract of descent, from the angle of the mandible to the upper mediastinum. Disruption of the thymic descent can result in ectopically/abnormally localised islets of accessory thymic tissue, which may undergo cystic changes, as described in a case report by Sun .
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