Atlantic salmon smolts were exposed to three doses of the fungicide azoxystrobin for 4 days, and physiological blood parameters and transcriptional effects in liver and muscle were evaluated in search for potential negative effects. Azoxystrobin exposure mediated up-regulation of catalase, MAPK1 and IGFBP1 in liver tissue. Catalase, transferrin, IGFBP1 and TNFR were up-regulated and CYP1A down-regulated in muscle tissue. Blood parameters glucose, hematocrit, pCO(2), HCO(3) and pH grouped together with transcripts levels of MnSOD, MAPK1, IGFBP1, MAP3K7 and GPx4 in liver of fish exposed to the highest azoxystrobin concentration (352 μgL(-1)) using principal component analysis (PCA). In muscle, the blood parameters glucose, hematocrit, pCO(2), HCO(3) and pH grouped together with transcript levels of heme oxygenase, thioredoxin, MnSOD, TNFR and MMP9. These results suggest that the fungicide azoxystrobin affects mitochondrial respiration and mechanisms controlling cell growth and proliferation in fish and may have negative effects on juvenile Atlantic salmon.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ecoenv.2010.07.017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bioactive Sesquiterpenoids from L. Flowers: Chemical Profiling and Antifungal Activity Against Species.
Plants (Basel)
January 2025
Department of Agricultural and Forestry Engineering, ETSIIAA, Universidad de Valladolid, Avenida de Madrid 44, 34004 Palencia, Spain.
L. (cotton-lavender) is receiving increasing attention due to its potential for modern medicine and is considered both a functional food and nutraceutical. In this work, the phytochemical profile of its flower hydromethanolic extract was investigated by gas chromatography-mass spectrometry, and its applications as a biorational for crop protection were explored against spp.
View Article and Find Full Text PDFThe Synergy of Chitosan and Azoxystrobin Against Is Modulated by Selected ABC Transporters.
Int J Mol Sci
December 2024
Plant Breeding and Acclimatization Institute-National Research Institute, Radzikow, 05-870 Blonie, Poland.
Article Synopsis
- Innovative strategies are needed to combat fungal pathogens for sustainable crop protection, with traditional fungicides facing resistance issues due to their single-target action.
- The study investigated the synergistic effects of chitosan (CS) and the fungicide azoxystrobin, finding a high synergy score that significantly improves antifungal efficacy.
- Additionally, combining CS and azoxystrobin with RNA interference techniques enhanced fungal control, highlighting a promising eco-friendly approach and the need for further research on its molecular mechanisms.
Pesticide Contamination of Honey-Bee-Collected Pollen in the Context of the Landscape Composition in Latvia.
Toxics
November 2024
Institute of Plant Protection Research 'Agrihorts', Latvia University of Life Sciences and Technologies, 2 Paula Lejiņa Street, LV-3004 Jelgava, Latvia.
The honey bee () is the most widely managed pollinator and is vital for crop fertilization. Recently, bee colonies have been suffering high mortality rates, exacerbated by factors such as land-use changes and the use of pesticides. Our work aimed to explore the residues of pesticides in honey-bee-collected pollen and how this contamination was affected by seasonality and the landscape composition.
View Article and Find Full Text PDFSensitivity Analysis of to Quinone-Outside Inhibitor and 14α-Demethylase Inhibitor Fungicides in Latvia.
Pathogens
December 2024
Latvian Biomedical Research and Study Centre, Ratsupites Street 1, k-1, LV-1067 Riga, Latvia.
Tan spot caused by is a severe threat to wheat production in all major wheat-growing regions. Sustainable tan spot control can be achieved by an integrated approach, including responsible management of fungicide sprays. The data about the sensitivity of to various fungicides in the Baltic Sea region are rare.
View Article and Find Full Text PDFBiological and Chemical Management of and Ochratoxin A in Vineyards.
Toxins (Basel)
December 2024
Department of Crop Science, Laboratory of Plant Pathology, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.
Ochratoxin A (OTA) is a widely distributed mycotoxin and potent carcinogen produced by several fungal genera, but mainly by . Grape contamination occurs in vineyards during the period between veraison and pre-harvest, and it is the main cause of OTA's presence in wine. The aim of the current study was the evaluation of 6 chemical and 11 biological plant protection products (PPPs) and biocontrol agents in commercial vineyards of the two important Greek white wine varieties cv.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!