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Clinical characteristics and booster vaccine effectiveness of the Omicron variant.
BMC Infect Dis
November 2024
Beijing Chest Hospital, Capital Medical University, Beijing, 101149, China.
Article Synopsis
- The study analyzed the characteristics and outcomes of COVID-19 patients during a Beijing Omicron outbreak, focusing on the impact of vaccination status on clinical severity and survival rates.
- Data was collected from 1495 cases, showing that vaccination, especially booster shots, significantly reduced disease severity and increased survival time compared to non-vaccinated individuals.
- Results indicated that elderly patients with pre-existing health conditions had a higher risk of severe illness and death, highlighting the importance of vaccination in this vulnerable population.
The Coronavirus Disease 2019 Pandemic and Time to Diagnosis for Childhood Pulmonary Diseases: Outcomes of a Tertiary Care Center.
Turk Arch Pediatr
July 2024
Department of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Coronavirus disease 2019 pandemic caused many changes in the social behaviors of individuals and the provision of health systems. Many studies revealed reductions in the number of diagnoses and delays in diagnosis time during the pandemic. This study aimed to evaluate the effect of the pandemic on the time to diagnosis of major diseases of pediatric pulmonology.
View Article and Find Full Text PDFApplication of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis.
Front Cell Infect Microbiol
July 2024
Department of Spine Surgery, Jiangbei Branch of Southwest Hospital, 958th Hospital of the PLA Army, Chongqing, China.
Objective: This study aimed to determine the sensitivity and specificity of metagenomic next-generation sequencing (mNGS) for detecting pathogens in spinal infections and to identify the differences in the diagnostic performance between mNGS and targeted next-generation sequencing (tNGS).
Methods: A total of 76 consecutive patients with suspected spinal infections who underwent mNGS, culture, and histopathological examinations were retrospectively studied. The final diagnosis of the patient was determined by combining the clinical treatment results, pathological examinations, imaging changes and laboratory indicators.
Venom Immunotherapy Does Not Affect Survival of Patients with Malignant Tumor in Poland.
J Clin Med
May 2024
Department of Allergology, Medical University of Gdańsk, 80-952 Gdańsk, Poland.
Allergen immunotherapy (AIT) is a well-established and efficient method of causative treatment for allergic rhinitis, asthma and insect venom allergy. Traditionally, a recent history of malignant neoplasm is regarded as a contraindication to AIT due to concerns that AIT might stimulate tumor growth. However, there are no data confirming that the silencing of the Th2 response affects prognosis in cancer.
View Article and Find Full Text PDFTimely Pulmonary Tuberculosis Diagnosis Based on the Epidemiological Disease Spectrum: Population-Based Prospective Cohort Study in the Republic of Korea.
JMIR Public Health Surveill
April 2024
Zarathu Co Ltd, Seoul, Republic of Korea.
Background: Timely pulmonary tuberculosis (PTB) diagnosis is a global health priority for interrupting transmission and optimizing treatment outcomes. The traditional dichotomous time-divided approach for addressing time delays in diagnosis has limited clinical application because the time delay significantly varies depending on each community in question.
Objective: We aimed to reevaluate the diagnosis time delay based on the PTB disease spectrum using a novel scoring system that was applied at the national level in the Republic of Korea.
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