AI Article Synopsis
- This study aimed to compare the effects of transcervical chorionic villus sampling (CVS) and amniocentesis on the occurrence of hemangiomas in infants.
- The research analyzed 250 procedures of each method, collecting data through questionnaires from parents, with follow-up physical examinations for children showing potential hemangiomas.
- Results indicated that CVS was linked to a significantly higher prevalence of hemangiomas (27.2%) compared to amniocentesis (9.4%), but no differences in congenital abnormalities were noted between the two procedures.
Article Abstract
Objectives: This study was designed to compare the effects of transcervical chorionic villus sampling (CVS) and amniocentesis on the prevalence of hemangiomas of infancy.
Methods: This is a cohort study of 250 consecutive assessable transabdominal amniocentesis procedures and 250 consecutive assessable transcervical CVS procedures performed between January and September 2002. Parents were asked to fill out a questionnaire regarding the presence of any type of skin lesions. Based on the responses to the questionnaire, children were invited to undergo a physical examination to confirm hemangiomas.
Results: Questionnaires were returned in 78% of the CVS group (195/250) and in 72% of the amniocentesis group (180/250). Based on the responses in the questionnaire, 78 children in the CVS group and 42 in the amniocentesis group underwent a physical examination. One or more hemangiomas were present in 53 of 195 (27.2%) children in the CVS group versus 17 of 180 (9.4%) children in the amniocentesis group (odds ratio 3.6, 95% CI: 2.0-6.5). There was no difference in congenital abnormalities between the two groups.
Conclusion: Transcervical CVS is associated with a significantly increased prevalence of hemangiomas compared with amniocentesis. The clinical features of these hemangiomas do not differ from natural hemangiomas and complications of these hemangiomas are very rare.
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| http://dx.doi.org/10.1002/pd.2562 | DOI Listing |
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