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Too little, too late? Extra anatomic aortic bypass for aortic coarctation in adults.
Ann Thorac Surg
January 2025
Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, 1700 6(th) Avenue South, Suite 9100, Birmingham, AL 35233. Electronic address:
Increased resting heart rate indicates high-workload hearts with augmented aortic hydraulic power in hypertensive pigs.
PLoS One
January 2025
Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Clarifying the inceptive pathophysiology of hypertensive heart disease helps to impede the disease progression. Through coarctation of the infrarenal abdominal aorta (AA), we induced hypertension in minipigs and evaluated physiological reactions and morpho-functional changes of the heart. Moderate aortic coarctation was achieved with approximately 30 mmHg systolic pressure gradient in minipigs.
View Article and Find Full Text PDFTranscriptome analysis of the aortic coarctation area.
J Mol Cell Cardiol Plus
December 2024
Department of Clinical Genetics, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Background: Coarctation of the aorta (CoA) is a relatively common congenital heart defect. The underlying causes are not known, but a combination of genetic factors and abnormalities linked to embryonic development is suspected. There are only a few studies of the underlying molecular mechanisms in CoA.
View Article and Find Full Text PDFDouble Transposition and Physician-Modified Endografting for Complex Arch Aneurysm.
Ann Thorac Surg Short Rep
September 2024
Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.
Hybrid repair of complex aortic arch disease typically requires aortic debranching to create a proximal landing zone for completion arch endografting. Despite advances in endograft technology, physician-modified endografting may be required to customize a prosthesis for challenging anatomy. We present a case of a complex distal arch aneurysm after a prior coarctation repair with a pediatric interposition graft several decades earlier, treated with hybrid repair by double transposition for arch debranching and physician-modified arch endografting for complete aneurysm exclusion.
View Article and Find Full Text PDFThird trimester fetal 4D flow MRI with motion correction.
Magn Reson Med
January 2025
Department of Radiology & Nuclear Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Purpose: To correct maternal breathing and fetal bulk motion during fetal 4D flow MRI.
Methods: A Doppler-ultrasound fetal cardiac-gated free-running 4D flow acquisition was corrected post hoc for maternal respiratory and fetal bulk motion in separate automated steps, with optional manual intervention to assess and limit fetal motion artifacts. Compressed-sensing reconstruction with a data outlier rejection algorithm was adapted from previous work.
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