The article drew attention to the construction of a vitamin B12 deficiency and its importance in the human body. Emphasizes the role of cobalamin as a structural element involved, among others cobamides in such reactions as the synthesis of purine and pyrimidine biosynthesis or choline. Two metabolically active forms of cobalamin: methylcobalamin and adenosylcobalamin and their importance to the human body were presented. The process of absorption of vitamin B12 and methionine in revealing the importance of the neurological symptoms was described. The chemical importance and cause vitamin B12 deficiency was stressed. The attention was paid upon the role of acid in methylomalon determination of vitamin B12 deficiency in the human body. Disclosure reports analyzed the relationship of vitamin B12 from the emergence of psychotic symptoms. Particular attention is given to teams which binds to the vitamin B12 deficiency--depressive, delusional and manic. Based on case reports were analyzed cases with deficiency symptoms associated with a deficit of vitamin B12. Also points to the possibility of diagnosing cobalamin deficiency even before the onset of clinical symptoms.
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