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Visualizing classification of drugs used in psychotic disorders: A 'subway map' representing mechanisms, established classes and informal categories.
J Psychopharmacol
September 2022
Geriatric Psychiatry Division, Centre for Addiction and Mental Health/University of Toronto, Toronto, ON, Canada.
Drugs used to treat psychotic disorders ('antipsychotics') have been widely used in psychiatry since the introduction of chlorpromazine in the mid-1950s. The categorization of these drugs evolved in a piecemeal way, relying initially on grouping by chemical structure (e.g.
View Article and Find Full Text PDF[Depression in the elderly. Medical treatment].
Presse Med
February 2001
Secteur 84.G.02, Centre Hospitalier de Montfavet, 2, avenue de la Pinède, BP 92, F 84128 Montfavet.
THE ADVENT OF DRUG THERAPY: In 1957, the advent of two compounds caught the attention of clinicians and psychopharmacologist: G 22355 or Tofranil, the leading drug in the tricyclic family, and iproniazid or Marsilid, a non-sedative monoamine oxidase inhibitor. WHAT IS AN ANTIDEPRESSOR DRUG?: Antidepressor drugs are not effective in all domains simultaneously: it takes 7 to 10 days before an effective equilibrium of mood is reached. Adverse effects often occur earlier, but generally fade out or are well tolerated when the antidepressor effect becomes patent.
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