The current study examines the effects of lateralized brain injury on Raven's Coloured Progressive Matrices (CPM) performance. Archival data on 106 unilateral brain-damage patients, 59 with right hemisphere damage and 47 with left, was utilized to examine four aspects of differential performance. Right brain-damaged subjects performed significantly lower than left brain-damaged subjects overall on the CPM. They also showed evidence of a higher incidence of and greater severity of hemi-neglect. After partialling out the effects of hemi-neglect, the subject groups were no longer significantly different on overall CPM performance. Evidence supporting the presence of heterogeneous subtests was not found. The results support the emerging pattern in research findings indicating that hemi-neglect plays a central role in differential performance. The CPM appears limited in its application and interpretation for patients with hemi-neglect.
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http://dx.doi.org/10.1016/s0010-9452(13)80316-4 | DOI Listing |
Gene
January 2025
Jiangxi Provincial Key Laboratory of Poultry Genetic Improvement, Nanchang 330032 China. Electronic address:
The growth and development of chicken skeletal muscle directly affects chicken meat production, which is very important for broiler industry. Matrix metallopeptidase 2 (MMP2) exists in skeletal muscle. However, the underlying regulating of MMP2 remain unknown.
View Article and Find Full Text PDFEur J Pain
March 2025
Department of Life Sciences, South Kensington, Imperial College London, London, UK.
Background: Healthy individuals demonstrate considerable heterogeneity upon dynamic quantitative sensory testing assessment of endogenous pain modulatory mechanisms. For those who stratify into a 'pro-nociceptive profile' cohort, consisting of inefficient conditioned pain modulation (CPM) and elevated temporal summation of pain (TSP), the optimal approach for balancing the net output of pain modulatory processes towards anti-nociception remains unresolved. In this translational healthy human and rat study, we examined whether descending modulation countered spinal amplification during concurrent application of a CPM and TSP paradigm alongside pupillometry since pontine activity was previously linked to functionality of endogenous pain modulatory mechanisms and pupil dilation.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
Shenzhen Neocurna Biotechnology Corporation, 12/F, Block B, Building 1, Yinxingzhijie Phase II, Longhua District, Shenzhen 518100, China.
The endosomal escape of lipid nanoparticles (LNPs) is crucial for efficient mRNA-based therapeutics. Here, we present a cationic polymeric micelle (cPM) as a safe and potent co-delivery system with enhanced endosomal escape capabilities. We synthesized a cationic and ampholytic di-block copolymer, poly (poly (ethylene glycol) methacrylate--hexyl methacrylate)--poly(butyl methacrylate--dimethylaminoethyl methacrylate--propyl acrylate) (p(PEGMA--HMA)--p(BMA--DMAEMA--PAA)), via reversible addition-fragmentation chain transfer polymerization.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue, Waterloo, ON N2L 3G1, Canada. Electronic address:
Chemically crosslinked foams possess good wet mechanical stability, and they are promising systems for applications in oil recovery, water treatment, energy storage, etc. However, reports on the effect of crosslinker length on the physical properties of the foam are scarce. Various cellulose nanofiber (CNF) foams (denoted as CPM) were prepared using different molecular weights dicarboxylated-PEG crosslinkers via the esterification reaction.
View Article and Find Full Text PDFLangmuir
January 2025
School of Physics and Electronic Science, Guizhou Normal University, Guiyang 550025, China.
The evolution of bifunctional catalysts for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) catalysts that are highly active, stable, and conductive is crucial for advancing metal-air batteries and fuel cells. We have here thoroughly explored the OER and ORR performance for a category of two-dimensional (2D) metal-organic frameworks (MOFs) called TM(HADQ), and Rh(HADQ) exhibits a promising bifunctional OER/ORR activity, with an overpotential of 0.31 V for both OER and ORR.
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