Introduction: Physical activity is a very important element in treatment of children with type 1 diabetes. However, it is difficult to find suitable exercises for the children due to their specific needs and psychophysiological condition. The aim of this study was to examine the effects of agility as a physical activity used to improve parameters of metabolic control in children with type 1 diabetes. Additionally, we hope that this form of recreation could induce a more health-oriented behavior in children.
Material And Methods: The experimental group consisted of seven girls aged 8-10 years, the patients of the Clinic of Pediatrics, Endocrinology, Diabetology, Metabolic Disorders and Cardiology of the Developmental Age in Szczecin. The children were qualified for the study after the prior assessment of their metabolic control under the conditions of the one-day hospital stay program. The physical condition of the patients was controlled with a 6-minute walk test and the test of perceived exertion (Borg scale). All the patients were treated using a personal insulin pump and the basal-bolus therapy. The applied research method used the scheme of physical exercise performed 3 times a week, 45 min each, reaching the intensity of 75% of the maximum heart rate under effort performed by a given patient. Before the exercises and directly after their completion, sugar level was measured in the blood of the patients (Accu-chek Active). During the exercises, the heart rate was measured with a pulsometer Bauer PM 80. The exercises included outdoor games and agility sessions. Especially the latter received a positive response and high involvement. This form includes a dog going through an obstacle course, with a child as a guide.
Results And Conclusions: After three months of the exercise scheme, the analysis of the collected results showed a statistically significant (p <0.05) decrease in the insulin doses (bolus) during morning hours (7-8 am), and in the evening at 9 pm and 10.30 pm, with an unchanged basal. No such decrease was observed in the control group. This study showed that an interesting physical activity resulted in a more eager and systematic effort among examined diabetic children. Its proper organization in time may help in the metabolic control in children with type 1 diabetes.
Download full-text PDF |
Source |
---|
Biol Trace Elem Res
January 2025
Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, Shijiazhuang 050071, Hebei, China.
Male infertility is a common complication of diabetes. Diabetes leads to the decrease of zinc (Zn) content, which is a necessary trace element to maintain the normal structure and function of reproductive organs and spermatogenesis. The purpose of this study was to investigate the effect of metformin combined with zinc on testis and sperm in diabetic mice.
View Article and Find Full Text PDFFam Cancer
January 2025
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disorder caused by a germline pathogenic variant in the MEN1 tumor suppressor gene. Patients with MEN1 have a high risk for primary hyperparathyroidism (PHPT) with a penetrance of nearly 100%, pituitary adenomas (PitAd) in 40% of patients, and neuroendocrine neoplasms (NEN) of the pancreas (40% of patients), duodenum, lung, and thymus. Increased MEN1-related mortality is mainly related to duodenal-pancreatic and thymic NEN.
View Article and Find Full Text PDFInflamm Res
January 2025
Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China.
Background: Allergic rhinitis (AR) represents a persistent inflammatory condition affecting the upper respiratory tract, characterized by abnormal initiation of the immunoglobulin E (IgE)-mediated cascade. Follicular helper T (Tfh) cells and regulatory T (Tfr) cells are pivotal in orchestrating the development of IgE production in AR patients. IL-35, an anti-inflammatory cytokine, secreted by various cellular subpopulations.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Endocrine, Genetics and Metabolism, Children's Hospital Affiliated to Xi'an Jiaotong University, Xi'an 710003, China.
Maturity-onset diabetes of the young (MODY) is a special type of diabetes characterized by clinical features including early onset of diabetes (before 30 years of age), autosomal dominant inheritance, impaired glucose-induced insulin secretion, and hyperglycemia. So far, 14 types of MODY have been reported, accounting for about 1%-5% of the patients with diabetes. MODY often presents with an insidious onset, and although 14 subtypes have been identified for MODY, it is frequently misdiagnosed as type 1 or type 2 diabetes due to overlapping clinical features and high costs and limitations of genetic testing.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology/Hubei Key Laboratory of Pediatric Genetic Metabolic and Endocrine Rare Diseases, Wuhan 430030, China.
Objectives: To study the clinical manifestations and genetic characteristics of children with maturity-onset diabetes of the young type 2 (MODY2), aiming to enhance the recognition of MODY2 in clinical practice.
Methods: A retrospective analysis was conducted on the clinical data of 13 children diagnosed with MODY2 at the Department of Pediatrics of Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology from August 2017 to July 2023.
Results: All 13 MODY2 children had a positive family history of diabetes and were found to have mild fasting hyperglycemia [(6.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!