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Revolutionizing Chronic Wound Treatment: Treating Bleomycin Intralesional Injection-Related Chronic Wounds with 3D Bioprinted Skin Substitutes.

J Invest Dermatol

January 2025

Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Department, PLA General Hospital and PLA Medical College; PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury, Repair and Regeneration; Research Unit of Trauma Care, Tissue Repair and Regeneration, Chinese Academy of Medical Sciences, 2019RU051, Beijing 100048, P. R. China. Electronic address:

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Background: Treatment of hypertrophic burn scars is challenging. Intralesional injection of corticosteroids has been the first line of treatment. Triamcinolone Acetonide (TA) and Bleomycin (BLE) are standard therapeutic options.

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This study evaluated the efficacy and safety of Intralesional Acyclovir in the treatment of recalcitrant palmoplantar and ungual warts in 14 patients(7 male and 7 female) of mean age 24.5 +- 8.19 years.

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