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| http://dx.doi.org/10.1155/2009/473047 | DOI Listing |
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Improving influenza forecast in the tropics and subtropics: a case study of Hong Kong.
J R Soc Interface
January 2025
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Influenza forecasts could aid public health response as shown for temperate regions, but such efforts are more challenging in the tropics and subtropics due to more irregular influenza activities. Here, we built six forecast approaches for influenza in the (sub)tropics, with six model forms designed to model seasonal infection risk (i.e.
View Article and Find Full Text PDFBetween 21 September and 6 December 2024, 657 highly pathogenic avian influenza (HPAI) A(H5N1) and A(H5N5) virus detections were reported in domestic (341) and wild (316) birds across 27 countries in Europe. Many HPAI outbreaks in domestic birds were clustered in areas with high poultry density and characterised by secondary farm-to-farm spread. Waterfowl, particularly the mute swan, were primarily affected during this reporting period, with HPAI virus detections focused on south-eastern Europe.
View Article and Find Full Text PDFEvidence of avian and human influenza A virus infection in farmed Siamese crocodiles (Crocodylus siamensis) in Thailand.
PLoS One
January 2025
Faculty of Veterinary Science, The Monitoring and Surveillance Center for Zoonotic Diseases in Wildlife and Exotic Animals, Mahidol University, Nakhon Pathom, Thailand.
Crocodilians are susceptible to a range of virus infection including influenza A virus (IAV). However, little is known about the ecology and epidemiology of IAV in crocodile species. This study aimed to investigate IAV infection in farmed Siamese crocodiles in central Thailand.
View Article and Find Full Text PDFComputationally Optimized Hemagglutinin Proteins Adjuvanted with Infectimune Generate Broadly Protective Antibody Responses in Mice and Ferrets.
Vaccines (Basel)
December 2024
Center for Vaccines and Immunology, University of Georgia, Athens, GA 30605, USA.
Standard-of-care influenza vaccines contain antigens that are typically derived from components of wild type (WT) influenza viruses. Often, these antigens elicit strain-specific immune responses and are susceptible to mismatch in seasons where antigenic drift is prevalent. Thanks to advances in viral surveillance and sequencing, influenza vaccine antigens can now be optimized using computationally derived methodologies and algorithms to enhance their immunogenicity.
View Article and Find Full Text PDFInter-city movement pattern of notifiable infectious diseases in China: a social network analysis.
Lancet Reg Health West Pac
January 2025
State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Background: Co-existence of efficient transportation networks and geographic imbalance of medical resources greatly facilitated inter-city migration of patients of infectious diseases in China.
Methods: To characterize the migration patterns of major notifiable infectious diseases (NIDs) during 2016-2020 in China, we collected migratory cases, who had illness onset in one city but were diagnosed and reported in another, from the National Notifiable Infectious Disease Reporting System, and conducted a nationwide network analysis of migratory cases of major NIDs at the city (prefecture) level.
Findings: In total, 2,674,892 migratory cases of NIDs were reported in China during 2016-2020.
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