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| http://dx.doi.org/10.2337/dc10-1043 | DOI Listing |
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Central hypothyroidism caused by roxadustat.
Tidsskr Nor Laegeforen
December 2024
Nyremedisinsk seksjon, Medisinsk klinikk, Sykehuset i Vestfold, Tønsberg.
Background: Isolated central hypothyroidism, although rare, has been documented in case reports in patients with chronic kidney disease (CKD) treated with roxadustat, a novel agent in the treatment of renal anaemia.
Case Presentation: A woman in her sixties with CKD stage 5 (not in dialysis) and no prior thyroid disease, was started on treatment with roxadustat 70 mg x 3 weekly for renal anaemia. During treatment, the patient developed classic signs of hypothyroidism (fatigue, dry skin, constipation, difficulty concentrating), with blood samples consistent with isolated central hypothyroidism.
Primary Thrombotic Microangiopathy in Pediatric Patients.
Glob Pediatr Health
December 2024
Universidad de Antioquia, Medellín, Colombia.
. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing , atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. .
View Article and Find Full Text PDFSurvival benefit of CPAP therapy among dialysis patients with obstructive sleep apnea.
Clin Exp Nephrol
December 2024
Nakamura Clinic, Urasoe, Okinawa, Japan.
Background And Hypothesis: We observed lower risk of all-cause mortally among continuous positive airway pressure (CPAP) users compared to those non-users using a large polysomnography (PSG) registry. However, the effect of CPAP on mortality risk has not been examined in dialysis patents.
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Chronic kidney disease-associated pruritus: a comparison of instruments and associations with patient-reported outcomes using an electronic patient-reported outcome survey in Europe.
Clin Kidney J
October 2024
Arbor Research Collaborative for Health, Ann Arbor, USA.
Background: The associations between self-reported chronic kidney disease-associated pruritus (CKD-aP) and patient-reported outcomes (PROs) have been reported using various instruments to assess itch. Data collection via multiple CKD-aP instruments allows the evaluation of different domains and measurements of CKD-aP burden and may help tailor data capture for future research or clinical care.
Methods: An electronic PRO (ePRO) survey was distributed to European hemodialysis (HD) patients enrolled in the Dialysis Outcomes and Practice Patterns Study (DOPPS) in 2021-23.
The "Silent" Threat: Group G Streptococcus Peritonitis in Peritoneal Dialysis.
Cureus
November 2024
Hospital Medicine, Cooper University Hospital, Camden, USA.
Peritoneal dialysis (PD) is a therapy for patients with end-stage renal disease (ESRD). PD carries an increased risk of peritonitis, often secondary to poor technique. A small subset of patients may present with "silent" peritonitis, or peritonitis in the absence of fever and abdominal pain, making diagnosis and treatment challenging.
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