The sanitary-hygienic well-being of 6 volunteers for the 105-d chamber experiment simulating some of the spaceflight factors was evaluated. To evaluate the pertinent means and methods, clinical, hygienic and microbiological investigations were employed, and volunteers' subjective opinions of personal hygiene items and associated procedures were analyzed Based on the examination of integument and oral cavity, entries in the questionnaires concerning subjective sensations, opinions and objective data, all volunteers were invariably in good state. Level of the skin total microbial contamination was found to depend on volunteers' diligence to fulfill the hygienic routine.

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