NMR analysis of complex mixtures can be significantly simplified using polyethyleneglycol (PEG) as resolving additive in DOSY NMR technique, which allows the extraction of individual spectra of mixture components with differing polarity. Resolving power of PEG-assisted DOSY was demonstrated with natural product mixtures.
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http://dx.doi.org/10.1002/mrc.2660 | DOI Listing |
Front Chem
February 2025
Faculty of Material Sciences, Shenzhen MSU-BIT University, Shenzhen, China.
Surface-enhanced Raman spectroscopy is a powerful analytical technique for the determination of analytes with the advantages of sensitivity, portability, and simplicity, able to provide structural information for the identification of compounds. However, when it comes to the analysis of complex samples, matrix components may interfere with the analyte quantification. To overcome this shortcoming, a number of approaches have been proposed, such as extraction techniques.
View Article and Find Full Text PDFMolecules
February 2025
Analytical Chemistry Division, Mintek, Private Bag X3015, Randburg 2125, South Africa.
Phosphorus is essential to environmental systems because it affects both agricultural productivity and ecological balance. Since it contributes to eutrophication and pollution problems, its existence in a variety of environmental matrices, including soil, water, and air, necessitates precise and effective determination methods for monitoring and managing its levels. This review paper provides an extensive overview of the latest advancements in analytical techniques for measuring phosphorus in environmental samples.
View Article and Find Full Text PDFJ Ethnopharmacol
March 2025
Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, China. Electronic address:
Unlabelled: ETHNIC PHARMACOLOGICAL RELEVANCE: "Cyathula officinalis Kuan (COK)" has the effect of "guiding the drug downward" and can enhance the efficacy of formula, e.g., Shentong Zhuyu Decoction (STZYD).
View Article and Find Full Text PDFBiomed Chromatogr
April 2025
School of Pharmacy, KPJ Healthcare University, Nilai, Negeri Sembilan, Malaysia.
Metformin has been a cornerstone in the management of type 2 diabetes mellitus (T2DM) for more than 50 years, either alone or in combination with other therapies. This oral antihyperglycemic agent, also known as dimethylbiguanide, plays a crucial role in regulating noninsulin-dependent diabetes mellitus and is widely prescribed globally for various medical conditions. Recent advancements in its formulations have aimed to increase its effectiveness, tolerance, and nonglycemic effects.
View Article and Find Full Text PDFJ Ovarian Res
March 2025
Department of Integrated Traditional & Western Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Background: Diminished ovarian reserve (DOR), a major cause of female infertility, is closely linked to insulin resistance (IR). Traditional Chinese Medicine (TCM) approaches, such as the Gengnianchun (GNC) formula, focus on restoring ovarian function by improving IR and regulating hormonal balance. Despite GNC's demonstrated efficacy, its precise therapeutic mechanisms remain unclear.
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