A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-alpha,beta-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257757PMC
http://dx.doi.org/10.3390/molecules15095928DOI Listing

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