Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.acvd.2009.11.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An exploration of unusual antimicrobial resistance phenotypes in Salmonella Typhi from Blantyre, Malawi reveals the ongoing role of IncHI1 plasmids.
Gates Open Res
January 2025
Liverpool School of Tropical Medicine, Liverpool, England, UK.
Typhoid fever is a significant public health problem endemic in Southeast Asia and Sub-Saharan Africa. Antimicrobial treatment of typhoid is however threatened by the increasing prevalence of antimicrobial resistant (AMR) Typhi, especially in the globally successful lineage (4.3.
View Article and Find Full Text PDFEnzymes enabling the biosynthesis of various C polyunsaturated fatty acids in a sea urchin .
Open Biol
January 2025
Department of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku , Tokyo 108-8477, Japan.
Sea urchins, integral to marine ecosystems and valued as a delicacy in Asia and Europe, contain physiologically important long-chain (>C) polyunsaturated fatty acids (PUFA) in their gonads, including arachidonic acid (ARA, 20:4n-6), eicosapentaenoic acid (EPA, 20:5n-3) and unusual non-methylene-interrupted fatty acids (NMI-FA) such as 20:2. Although these fatty acids may partially be derived from their diet, such as macroalgae, the present study on has uncovered multiple genes encoding enzymes involved in long-chain PUFA biosynthesis. Specifically, 3 fatty acid desaturases (FadsA, FadsC1 and FadsC2) and 13 elongation of very-long-chain fatty acids proteins (Elovl-like, Elovl1/7-like, Elovl2/5-like, Elovl4-like, Elovl8-like and Elovl6-like A-H) were identified in their genome and transcriptomes.
View Article and Find Full Text PDFFlipons and the origin of the genetic code.
Biol Lett
January 2025
Discovery, InsideOutBio , Charlestown, MA, USA.
This paper is focused on the origins of the contemporary genetic code. A novel explanation is proposed for how the mapping of nucleotides in DNA to amino acids in proteins arose that derives from repeat nucleotide sequences able to form alternative nucleic acid structures (ANS), such as the unusual left-handed Z-DNA, triplex, G-quadruplex and I-motif conformations. The scheme identifies sequence-specific contacts that map ANS repeats to dipeptide polymers (DPS).
View Article and Find Full Text PDFPlant mitochondrial and plastid genomes have exceptionally slow rates of sequence evolution, and recent work has identified an unusual member of the gene family ("plant ") as being instrumental in preventing point mutations in these genomes. However, the eXects of disrupting -mediated DNA repair on "germline" mutation rates have not been quantified. Here, we used mutation accumulation (MA) lines to measure mutation rates in mutants and matched wild type (WT) controls.
View Article and Find Full Text PDFRapid detection of RNase-based self-incompatibility in Lysimachia monelli (Primulaceae).
Am J Bot
January 2025
Department of Biological Sciences, University of Illinois at Chicago, Chicago, 60607, IL, USA.
Premise: Primroses famously employ a system that simultaneously expresses distyly and filters out self-pollen. Other species in the Primulaceae family, including Lysimachia monelli (blue pimpernel), also express self-incompatibility (SI), but involving a system with distinct features and an unknown molecular genetic basis.
Methods: We utilize a candidate-based transcriptome sequencing (RNA-seq) approach, relying on candidate T2/S-RNase Class III and S-linked F-box-motif-containing genes and harnessing the unusual evolutionary and genetic features of SI, to examine whether an RNase-based mechanism underlies SI in L.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!