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Desmoplastic small round cell tumor of the kidney: a case report and discussion.
Front Oncol
June 2024
Department of Pediatric Surgery, The First Affiliated Hospital of Xiamen University, Xiamen University, Xiamen, Fujian, China.
A 13-year-old boy was admitted to the hospital with 1-month history of neck pain and a 2-week history of bilateral hip joint pain accompanied by low fever. Positron emission tomography-computed tomography (PET-CT) revealed the presence of a malignant tumor in the left kidney with metastases to the left renal hilum, retroperitoneum, para-aortic lymph nodes, and multiple bone sites throughout the body. Given that the patient's left kidney capsule was intact and the boundary with surrounding tissues was clear, left nephrectomy was performed.
View Article and Find Full Text PDFProblems and countermeasures for surgical resection of primary pulmonary artery intimal sarcoma.
Transl Cancer Res
February 2023
Department of General Thoracic Surgery, Juntendo University Hospital, Tokyo, Japan.
Article Synopsis
- Pulmonary artery intimal sarcoma (PAIS) is a rare and aggressive type of cancer, and this study investigated surgical treatment outcomes by reviewing 10 patient cases from 2007 to 2020.
- Surgical strategies included pulmonary resection, vascular replacement, and pulmonary endarterectomy, with a high recurrence rate of 89% and a median survival of 15 months post-surgery.
- The study recommends thorough surgical margins of at least 20 mm and emphasizes the need for close follow-up for potential recurrence within one year after surgery.
An innovative systematic approach introduced the involved lncRNA-miR-mRNA network in cell cycle and proliferation after conventional treatments in breast cancer patients.
Cell Cycle
August 2022
Department of Clinical Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
The present study aimed to explore the involved lncRNA-miRNA-mRNA network in the cell cycle and proliferation after conventional treatments in Luminal A breast cancer patients.The candidate miRNAs (miRs), lncRNAs, and mRNAs were first taken from the Gene Expression Omnibus and TCGA databases. The lncRNA-miR-mRNA network was then constructed using the high-throughput sequencing data.
View Article and Find Full Text PDFCase Report: Chemotherapy Indication in a Case of Neurofibromatosis Type 1 Presenting Optic Pathway Glioma: A One-Year Clinical Case Study Using Differential Tractography Approach.
Front Hum Neurosci
April 2021
Functional Neurosurgery Research Center, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Neurofibromatosis type 1 (NF1) is associated with peripheral and central nervous system tumors. It is noteworthy that the regions in which these tumors frequently arise are the optic pathways (OPs) and the brainstem. Thus, we decided to trace the procedure of diffusion Magnetic Resonance Imaging (dMRI) alterations along with Short-Wavelength Automated Perimetry (SWAP) examinations of the OPs after surgery and chemotherapy over 1 year, which enabled us to evaluate chemotherapy's efficacy in an NF1 patient with an OP tumor.
View Article and Find Full Text PDF[A Case Report of Primary Pulmonary NUT Carcinoma and Literature Review].
Zhongguo Fei Ai Za Zhi
January 2021
Department of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu 610041, China.
Article Synopsis
- NUT carcinoma is a rare and aggressive cancer linked to a genetic rearrangement on chromosome 15, often resulting in poor prognosis and typically occurring in central locations of the body, such as the lungs.
- A case of a 70-year-old man diagnosed with primary pulmonary NUT carcinoma is described, with a tumor detected in the left lung during routine examination.
- The patient underwent surgery followed by chemotherapy, antiangiogenesis therapy, and radiotherapy, which contributed to an extended lifespan, highlighting the clinical features and treatment approaches for this uncommon disease.
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