As a result of the proposed study it was established that a complex action of carbon oxide and toluene++ in 300 mg/m3 concentration in a combination with heating microclimate (leading to a maximum heat labour condition) results in an increased total biological effect. The coefficient to the complex action of carbon oxide and heating microclimate is equal to 2.5 and toluene++ and heating microclimate to 1.9. These coefficients should be taken into account in establishing hygienic norms for the chemical compounds.

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