Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367787 | PMC |
| http://dx.doi.org/10.1136/bmj.1.3760.140 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transient Receptor Potential Melastatin 8 Contributes to Cystitis-Induced Neuronal Sprouting and Pain Hypersensitivity Through AKT/mTOR Signaling Pathway in Interstitial Cystitis/Bladder Pain Syndrome.
Low Urin Tract Symptoms
November 2024
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Objectives: The aim of this study was to investigate the mechanism of TRPM8 in neuroproliferation and pain, as well as the relevance of the Akt/mTOR signaling pathway in mice with IC/BPS.
Methods: The model of IC/BPS was established in wild and TRPM8 mice. The mechanical sensitivity was measured.
Inhibiting the JNK Signaling Pathway Attenuates Hypersensitivity and Anxiety-Like Behavior in a Rat Model of Non-specific Chronic Low Back Pain.
J Mol Neurosci
July 2024
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230000, Anhui Province, China.
Low back pain (LBP) has become a leading cause of disability worldwide. Astrocyte activation in the spinal cord plays an important role in the maintenance of latent sensitization of dorsal horn neurons in LBP. However, the role of spinal c-Jun N-terminal kinase (JNK) in astrocytes in modulating pain behavior of LBP model rats and its neurobiological mechanism have not been elucidated.
View Article and Find Full Text PDFA novel animal model of symptomatic neuroma for assessing neuropathic pain.
Neurosci Lett
July 2024
Department of Surgery, Section of Plastic Surgery, The University of Michigan Health System, Ann Arbor, MI, United States; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI, United States. Electronic address:
Introduction: Following amputation, peripheral nerves lack distal targets for regeneration, often resulting in symptomatic neuromas and debilitating neuropathic pain. Animal models can establish a practical method for symptomatic neuroma formation for better understanding of neuropathic pain pathophysiology through behavioral and histological assessments. We created a clinically translatable animal model of symptomatic neuroma to mimic neuropathic pain in patients and assess sexual differences in pain behaviors.
View Article and Find Full Text PDFEffects of a novel osteopathic visceral technique for the pancreas on pain and range of motion in a patient with neck pain: Case report.
J Bodyw Mov Ther
July 2024
School of Osteopathy of Madrid, Rua do Ameal, N.°230 R/C Esq., 4900-585 Viana do Castelo, Portugal. Electronic address:
Introduction: Neck pain is a leading cause of disability worldwide. Visceral referred pain is a common form of disease-induced pain, with visceral nociception being referred to somatic tissues.
Objective: The aim of this case report was to evaluate the immediate and long term effects of a novel osteopathic visceral technique (OVT) on pain and cervical range of motion (CROM) in a patient with nonspecific neck pain (NS-NP).
Widespread Pressure Pain Hyperalgesia Is Not Associated With Morphological Changes of the Wrist Extensor Tendon in Unilateral Lateral Epicondylalgia: A Case-Control Study.
Phys Ther
September 2024
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, Alcorcón, Spain.
Article Synopsis
- This study aimed to explore the existence of widespread pain sensitivity (hyperalgesia) and structural changes in wrist tendons and muscles in individuals with lateral epicondylalgia (LE).
- Thirty-seven LE patients, along with 37 pain-free controls, were assessed for pressure pain thresholds and underwent ultrasound evaluations to measure changes in tendon and muscle structure.
- Results showed that LE patients had significantly lower pain thresholds and notable structural changes in the wrist extensor tendon compared to controls, but these changes were unrelated to each other in terms of pain sensitivity.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!