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Rev Med Suisse
January 2025
iEH2 - Institut éthique histoire humanités, CMU, Université de Genève, 1211 Genève 4.
Trust is a particularly important element in a healthcare relationship, but it is often misunderstood. In this article, we explore the trust relationship between patients and healthcare professionals and the expectations underpinning it. We then look at some of the expectations of trans* people in the context of medical consultations that are not related to medical transition.
View Article and Find Full Text PDFFront Immunol
January 2025
Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner", (INIBIOLP), Universidad Nacional de La Plata (UNLP) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), La Plata, Argentina.
Introduction: Gastropod hemocyanins are potent immunostimulants in mammals, a trait associated with their large molecular size and unusual glycosylation patterns. While the hemocyanin from the marine snail keyhole limpet (KLH), has been widely studied and successfully employed as a carrier/adjuvant in several immunological applications, as well as a non-specific immunostimulant for bladder cancer treatment, few other gastropod hemocyanins have been biochemically and immunologically characterized. In this work, we investigated the immunogenic properties of the hemocyanin from (PcH), an invasive south American freshwater snail.
View Article and Find Full Text PDFActa Endocrinol (Buchar)
January 2025
Basaksehir Cam and Sakura City Hospital, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey.
Background: The aim of this study was to assess the awareness of the USA and world population about osteoporosis, taking into account seasonal variations and economic conditions.
Methods: The term "osteoporosis" was searched using Google Trends between January 1, 2004 and September 12, 2024. Cosinor analysis was used to test the effect of seasonality on relative search volumes (RSV) for osteoporosis searches in the USA and worldwide.
Constraints
November 2024
Polytechnique Montréal, Montreal, Canada.
Constraint programming is known for being an efficient approach to solving combinatorial problems. Important design choices in a solver are the , designed to lead the search to the best solutions in a minimum amount of time. However, developing these heuristics is a time-consuming process that requires problem-specific expertise.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Plastic and Reconstructive Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, People's Republic of China.
Cutaneous melanoma is one of the most aggressive skin cancers originating from skin pigment cells. Patients with advanced melanoma suffer a poor prognosis and generally cannot benefit well from surgical resection and chemo/target therapy due to metastasis and drug resistance. Thus, adoptive cell therapy (ACT), employing immune cells with specific tumor-recognizing receptors, has emerged as a promising therapeutic approach to display on-tumor toxicity.
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