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Clinico-hematological and immunophenotypic profile of acute leukemia of ambiguous lineage: A four year experience from a single tertiary care centre of West India.
Indian J Pathol Microbiol
February 2024
Oncopathology Department, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
Background: : Acute leukemia of ambiguous lineage (ALAL) is a heterogeneous group of rare leukemias that lacks definite evidence of differentiation along one lineage. It includes acute undifferentiated leukemia and mixed-phenotype acute Leukaemia (MPAL).
Aims: The present study highlighted the clinicohematological and immunophenotypic profile of ALAL cases diagnosed in the tertiary care centre of western India.
Clinico-Hematological Profile of Acute Myeloid Leukemia: Experience From a Tertiary Care Cancer Center in North India.
Cureus
December 2023
Clinical Research Unit, All India Institute of Medical Sciences, New Delhi, IND.
Introduction: Complete diagnosis of acute myeloid leukemia (AML) requires knowledge of clinical information combined with morphologic evaluation, immunophenotyping, karyotyping, and molecular genetic testing. The study intends to evaluate the demographic profile, clinical workup, and investigation, including flow cytometric immunophenotyping, in adult and pediatric age groups of AML.
Materials And Methods: This is a retrospective study of AML patients treated between January 2017 and December 2021.
Morphological Spectrum of Bone Marrow Aspirates in Infections: A Clinico-Hematological Analysis.
J Microsc Ultrastruct
September 2023
Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.
Context: Bone marrow examination (BME) is an invaluable tool for cases with pyrexia of unknown origin and pancytopenia. However, it is under-utilized for diagnosing infectious etiology and there is a paucity of literature regarding its role in infective pathology.
Aims: This study aims to bring to light the role of BME in diagnosing infectious pathology.
Clinico-Hematological Profile and Management of Children With Non-Transfusion Dependent Thalassemia (NTDT) at a Pediatric Center in Northern India.
Indian Pediatr
August 2023
Department of Pediatrics, Kalawati Saran Children's Hospital, New Delhi.
Objective: To study the clinico-hematological profile, complications, and management of children with non-transfusion dependent thalassemia (NTDT) in northern India.
Method: We retrieved and analyzed the data of 69 children with NTDT diagnosed between January, 2006 to December, 2018, aged under 18 years from our unit's records.
Results: The participants mean (SD) age was 4.
Clinical, Hematological, and Cytogenetic Profile of Myelodysplastic Syndromes in Adults: A Three-year Cross-sectional Study.
Oman Med J
March 2023
Department of Clinical Hematology and Hemato-oncology, Rajagiri Hospital, Kochi, India.
Objectives: Myelodysplastic syndromes (MDS) are a group of clonal hematological disorders with a diverse clinico-hematological profile. Studies in India have shown a different biology from the West. This study aimed to assess the clinicopathologic profile of MDS patients, classify them according to the World Health Organization classification system, categorize them into International Prognostic Scoring System (IPSS) and the revised IPSS prognostic subgroups, and evaluate the treatment outcome.
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