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Ectopic Atrial Beats May Cause a ZigZag Pattern at Intrapartum Recording of the Fetal Heart Rate Using Fetal Scalp Electrode.
Fetal Diagn Ther
December 2024
Department of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.
Introduction: Fetal scalp electrode (FSE) is considered the gold standard for the intrapartum monitoring of the fetal heart rate (FHR) being associated with the lowest rate of signal loss and artifacts including the recording of the maternal heart rate. FSE acquires a fetal electrocardiogram and evaluates the time intervals between successive R waves. As such, it allows the recording of the beat-to-beat fluctuation of the FHR.
View Article and Find Full Text PDFTypes of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study.
Acta Obstet Gynecol Scand
November 2022
Obstetrics Center, Jeanne de Flandre Hospital, CHRU Lille, Lille, France.
Article Synopsis
- The study aimed to classify different types of hypoxia in neonates with metabolic acidemia and track the progression of fetal heart rate abnormalities.
- It included 132 neonates, focusing on those with gradually evolving hypoxia, and assessed heart rate changes using the FIGO classification.
- Results showed that gradually evolving hypoxia was the most common (47%), with deceleration being the first heart rate abnormality to occur in the majority of cases.
Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure.
Biomedicines
March 2022
Department of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
The pathogenesis of multiple sclerosis (MS) remains enigmatic and controversial. Myelin sheaths in the central nervous system (CNS) insulate axons and allow saltatory nerve conduction. MS brings about the destruction of myelin sheaths and the myelin-producing oligodendrocytes (ODCs).
View Article and Find Full Text PDFIntrapartum zigzag pattern of fetal heart rate is an early sign of fetal hypoxia: A large obstetric retrospective cohort study.
Acta Obstet Gynecol Scand
February 2021
Department of Obstetrics and Gynecology, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland.
Introduction: The aim of the present study was to identify possible associations of fetal heart rate (FHR) patterns during the last 2 hours of labor with fetal asphyxia expressed by umbilical artery acidemia at birth and with neonatal complications in a large obstetric cohort.
Material And Methods: Cardiotocographic recordings from 4988 singleton term childbirths over 1 year were evaluated retrospectively and blinded to the pregnancy and neonatal outcomes in a university teaching hospital in Helsinki, Finland. Umbilical artery pH, base excess and pO , low Apgar scores at 5 minutes, need for intubation and resuscitation, early neonatal hypoglycemia, and neonatal encephalopathy were used as outcome variables.
Genomics and High-Resolution Typing Confirm Predominant Clonal Evolution Down to a Microevolutionary Scale in .
Pathogens
May 2020
Catedra Francisco Jose Ayala of Science, Technology, and Religion, University of Comillas, 28015 Madrid, Spain.
, the agent of Chagas disease, is a paradigmatic case of the predominant clonal evolution (PCE) model, which states that the impact of genetic recombination in pathogens' natural populations is not sufficient to suppress a persistent phylogenetic signal at all evolutionary scales. In spite of indications for occasional recombination and meiosis, recent genomics and high-resolution typing data in reject the counterproposal that PCE does not operate at lower evolutionary scales, within the evolutionary units (=near-clades) that subdivide the species. Evolutionary patterns in the agent of Chagas disease at micro- and macroevolutionary scales are strikingly similar ("Russian doll pattern"), suggesting gradual, rather than saltatory evolution.
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