The seeding of 6 mm Dacron prostheses with microvascular endothelial cells from omental adipose tissue leads to endothelialized prostheses, 5 weeks later with a complete coverage of functional and thrombus free endothelium. The method is ready for clinical trials.
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Radiology
December 2024
From the Centro Cardiologico Monzino, IRCCS, Via C. Belgioioso 173, Milan, Italy (D.A., S.M., D.T., E.C., G.L., S. Galli, G.M., L.G., G.T., S.T., S. Gili, P.M., P.O., V.M., D.M., M.S., C.G., E.M., A.B., M.E.M., A.A., A F., G.P., A.L.B.); Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy (D.A.); IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy (E.C., G.M., L.G., V.M., D.M., M.S., E.G., P.P., E.M., A.L.B.); Cardiovascular Center Aalst, OLV Hospital, Aalst, Belgium (J.S., M.B., E.G., P.P., K.S., T.M., C.C.); Department of Medicine, Division of Cardiology, Showa University School of Medicine, Tokyo, Japan (K.S., T.M.); Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy (G.P.); and Department of Radiology, Azienda Ospedaliera di Padova, Padua, Italy (L.Z.).
Background The detection of in-stent restenosis (ISR) with coronary CT angiography (CCTA) is challenging, but CT perfusion (CTP) has demonstrated improved diagnostic accuracy over CCTA in patients with stents. However, there are limited data on the performance of dynamic CTP, which allows noninvasive adjudication of regional myocardial blood flow. Purpose To compare the diagnostic performance of regadenoson-stress dynamic CTP with that of CCTA, using fractional flow reserve (FFR) and the index of microvascular resistance (IMR) as reference standards for epicardial coronary circulation and coronary microcirculation, respectively.
View Article and Find Full Text PDFCatheter Cardiovasc Interv
January 2025
Pediatrics & Medicine, Weill Cornell Medicine Chief International Patients Services & Chair, Sidra Department Cardiovascular Diseases, University of Jordan, Amman, Jordan.
Cardiovasc Intervent Radiol
January 2025
Department of Radiology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Purpose: This study aims to present our experience with superselective embolization of the anterior spinal artery-bearing segmental artery (ASAbSA) using a microvascular plug (MVP) during the minimally invasive segmental artery coil embolization (MISACE) procedure prior endovascular repair of the thoracoabdominal aortic aneurysms.
Methods: We retrospectively evaluated all MISACE procedures performed between May 2018 and July 2023, where MVP was deployed into an angiographically confirmed ASAbSA. Data were analyzed regarding interventional details, technical aspects, and safety protocols.
ACS Appl Mater Interfaces
December 2024
Faculty of Materials Sciences and Engineering, Warsaw University of Technology, Warsaw 02-507, Poland.
The microvascular bed plays a crucial role in establishing nutrient exchange and waste removal, as well as maintaining tissue metabolic activity in the human body. However, achieving microvascularization of engineered 3D tissue constructs is still an unsolved challenge. In this work, we developed biomimetic cell-laden hydrogel microfibers recapitulating oriented microvascular capillary-like networks by using a 3D bioprinting technique combined with microfluidics-assisted coaxial wet-spinning.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Burns, Nanfang Hospital, Southern Medical University, Jingxi Street, Baiyun District, Guangdong 510515, China. Electronic address:
Adequate vascularization essential for delivering nutrients critical to wound healing, yet impaired angiogenesis is a major barrier in diabetic wound repair. This study investigates the impact of hyaluronic acid on interpenetrating network sponge scaffolds derived from an acellular dermal matrix, with the aim of enhancing vascularization and healing of diabetic wounds via photothermal warm bath therapy. We prepared three-dimensional porous sponges (HPD@DFO) using molecular interpenetration and ion crosslinking of porcine acellular dermal matrix (PADM), hyaluronic acid, and polydopamine nanoparticles loaded with deferoxamine mesylate (PDA@DFO).
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