Lactating dams of WAG/Rij and Wistar rat strains were repeatedly placed on the "open field" arena with their pups (4-9 postnatal days). In these conditions WAG/Rij rats showed significantly poorer maternal behavior and were slower in forming pup location response. These results add to the notion of disorders in the activity of the nervous system of WAG/Rij rats (as genetic models for absence epilepsy). Administration of Haloperidol in a low dose (0.1 mg/kg, i.p.) reduced the motor activity ofdams of both strains and maternal behavior under conditions of bright illumination. Under conditions of red-light illumination, haloperidol increased the number of approaches to the pups and the number of their transportations in WAG/Rij (but not Wistar) rats and reduced the latencies of the behavioral reactions. It is suggested that dopaminergic regulation of maternal behavior depends on both genetic (strain differences) and environmental (illumination conditions) factors.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Inter-Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five-Nations Survey Study.
United European Gastroenterol J
January 2025
Sheba Medical Center, Institute of Gastroenterology, Ramat-Gan, Israel.
Background: The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointestinal tract and perianal involvement. With evolving management paradigms in Crohn's disease, we aimed to assess the performance of gastroenterologists in applying the Montreal classification.
Methods: An online survey was conducted among participants at an international educational conference on inflammatory bowel diseases.
Objective: The neuropsychological adverse effects of antiseizure medications (ASMs) influence the tolerability, and in turn effectiveness of these medications, which can occur in a dose-dependent fashion. In this study, we examine the neuropsychological effects of perampanel (PER) at 4 mg daily as this dose has not been previously assessed with objective cognitive tests.
Methods: The study was originally designed to assess (1) effects of perampanel at 4 mg using different titration rates, and (2) habituation over time.
Correction: Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring's -Exploring the Molecular Mechanism.
Mol Neurobiol
January 2025
Nitte (Deemed to be University), Department of Physiology, KS Hegde Medical Academy, Deralakatte, Mangalore, Karnataka, 575018, India.
Early parent-child interaction and home environments of children exposed prenatally to opioids: A comparison of biological mothers and out-of-home caregivers.
Infant Ment Health J
January 2025
Canterbury Child Development Research Group, University of Canterbury, Christchurch, New Zealand.
Children born to mothers with opioid use disorder (OUD) are at increased risk of maltreatment and out-of-home care (OOHC) placement. This study examines the parent-child interaction quality and home environments of 92 New Zealand children with prenatal opioid exposure (OE) and 106 non-opioid-exposed (NE) children. Experiences for those in maternal care versus OOHC were of particular interest.
View Article and Find Full Text PDFPregnancy entails a U-shaped trajectory in human brain structure linked to hormones and maternal attachment.
Nat Commun
January 2025
Unitat de Recerca en Neurociència Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autònoma de Barcelona, Barcelona, Spain.
Growing evidence places the gestational period as a unique moment of heightened neuroplasticity in adult life. In this longitudinal study spanning pre, during, and post pregnancy, we unveil a U-shaped trajectory in gray matter (GM) volume, which dips in late pregnancy and partially recovers during postpartum. These changes are most prominent in brain regions associated with the Default Mode and Frontoparietal Network.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!