Aryl(sulfonyl)amino group: a convenient and stable yet activated modification of amino group for its intramolecular displacement.

Org Lett

Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259-B-59 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.

Published: September 2010

Aryl(sulfonyl)amino groups, readily derived from sulfonyl- or arylamines by standard methods as well as the recently introduced methods of sulfonylation and arylation, proved to be good leaving groups in intramolecular substitution reactions by various nitrogen, oxygen, and carbon nucleophiles.

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Source
http://dx.doi.org/10.1021/ol101541pDOI Listing

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