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The B Chromosome of Pseudococcus viburni: A Selfish Chromosome that Exploits Whole-Genome Meiotic Drive.
Genome Biol Evol
January 2025
School of Biological Sciences, Institute of Ecology and Evolution, The University of Edinburgh, Edinburgh EH9 3FL, UK.
Meiosis is generally a fair process: each chromosome has a 50% chance of being included into each gamete. However, meiosis can become aberrant with some chromosomes having a higher chance of making it into gametes than others. Yet, why and how such systems evolve remains unclear.
View Article and Find Full Text PDFWhy work in another country? Japanese nurses' experience and their reasons for staying in Australia.
Jpn J Nurs Sci
January 2025
Graduate School of Medicine, Osaka University, Osaka, Japan.
Aim: Many Japanese nurses have moved to Australia, yet their experiences and perceived reasons for staying in Australia are understudied. This study identified why Japanese nurses who moved internationally to Australia continued to stay and work in Australia.
Methods: Semi-structured interviews were conducted with 15 Japanese nurses who hold Japanese nursing licenses and are registered as nurses in Australia.
Evaluating Computerised Assessment of Motor Imitation (CAMI) for identifying autism-specific difficulties not observed for attention-deficit hyperactivity disorder or neurotypical development.
Br J Psychiatry
January 2025
Department of Psychology, Nottingham Trent University, UK; and Institute of Human Sciences, University of Oxford, UK.
Background: Reliable and specific biomarkers that can distinguish autism spectrum disorders (ASDs) from commonly co-occurring attention-deficit/hyperactivity disorder (ADHD) are lacking, causing misses and delays in diagnosis, and reducing access to interventions and quality of life.
Aims: To examine whether an innovative, brief (1-min), videogame method called Computerised Assessment of Motor Imitation (CAMI), can identify ASD-specific imitation differences compared with neurotypical children and children with ADHD.
Method: This cross-sectional study used CAMI alongside standardised parent-report (Social Responsiveness Scale, Second Edition) and observational measures of autism (Autism Diagnostic Observation Schedule-Second Edition; ADOS-2), ADHD (Conners) and motor ability (Physical and Neurological Examination for Soft Signs).
Diabetes Mellitus Impairs Blood-Brain Barrier Integrality and Microglial Reactivity.
J Biophotonics
January 2025
Britton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Diabetes mellitus (DM), a chronic metabolic disorder that adversely affects the blood-brain barrier (BBB) and microglial function in the central nervous system (CNS), contributing to neuronal damage and neurodegenerative diseases. However, the underlying molecular mechanisms linking diabetes to BBB dysfunction and microglial dysregulation remain poorly understood. Here, we assessed the impacts of diabetes on BBB and microglial reactivity and investigated its mechanisms.
View Article and Find Full Text PDFDoes pregnancy in adolescence increase the chances of osteoporosis among aged women? Findings from the ELSI study.
Australas J Ageing
March 2025
Faculty of Nutrition, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.
Objective: Bone mineral density changes during the life span, rising rapidly during adolescence, plateauing around 30 years of age and decreasing in later years. Life events such as pregnancy and lactation temporarily reduce bone density, and their long-term effects on osteoporosis development are still unclear. This study aimed to analyse the association between pregnancy in adolescence and osteoporosis in aged women.
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