Purpose: To assess the pain course after intraarticular injection of a gadolinium-containing contrast material admixed with anesthetic for magnetic resonance (MR) arthrography of the shoulder in relation to internal derangements of the shoulder.
Materials And Methods: Institutional review board approval and informed consent were obtained for this study. The study sample consisted of 655 consecutive patients (249 female, 406 male; median age, 54 years) referred for MR arthrography of the shoulder. Pain level was measured at baseline, directly after intraarticular injection of the gadolinium-containing contrast material admixed with anesthetic, 4 hours after injection, 1 day (18-30 hours) after injection, and 1 week (6-8 days) after injection with a visual analog scale (range, 0-10). MR arthrography was used to assess the following internal derangements: lesions of the rotator cuff tendons and long biceps tendon, adhesive capsulitis (frozen shoulder), fluid in the subacromial bursa, labral tears, and osteoarthritis of the glenohumeral joint. History of shoulder surgery was recorded. Linear regression models were calculated for the dependent variable (difference between follow-up pain and baseline pain), with the independent variable grouping adjusted for age and sex.
Results: There was no significant association between pain level over time and internal derangements of the shoulder, nor was there significant association between pain level over time in patients with a history of shoulder surgery and patients without a history of shoulder surgery.
Conclusion: Neither internal derangements nor prior surgery have an apparent effect on the pain course after MR arthrography of the shoulder.
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http://dx.doi.org/10.1148/radiol.10091671 | DOI Listing |
Crit Care Explor
December 2024
Department of Anaesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.
Objectives: To evaluate the base excess response during acute in vivo carbon dioxide changes.
Design: Secondary analysis of individual participant data from experimental studies.
Setting: Three experimental studies investigating the effect of acute in vivo respiratory derangements on acid-base variables.
Cureus
November 2024
Internal Medicine, Northumbria Healthcare NHS Trust, Newcastle-Upon-Tyne, GBR.
We present a rare and challenging case of Weil's disease in a patient who was admitted to the Critical Care Unit with a clinical suspicion of the condition. The patient showed a prompt response to treatment before laboratory confirmation was obtained. Leptospirosis, a zoonotic disease, is most commonly found in tropical and temperate regions.
View Article and Find Full Text PDFJ Ayurveda Integr Med
December 2024
Department of Kayachikitsa, All India Institute of Ayurveda, New Delhi, 110076, India. Electronic address:
Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy marked by the clonal proliferation of the mature, yet dysfunctional B lymphocytes in blood and its subsequent infiltration of the marrow, lymphoid tissues and spleen. The resultant immune dysfunction exposes the body to multiple infections and is a cause of major mortality. Here, we discuss the case of a 46-year-old male suffering from CLL who presented with long-standing episodes of low-grade fever, productive cough and throat irritation, lethargy and pedal edema.
View Article and Find Full Text PDFFront Immunol
December 2024
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks. The pathogenesis of HS is not fully understood, but considering the key role played by the biological clock in the control of immune/inflammatory processes the derangement of circadian and ultradian pathways could be hypothesized.
Methods: We analyzed genome-wide DNA methylation patterns in peripheral blood from 24 HS cases and 24 controls using the Infinium HumanMethylation450 BeadChip array (Illumina), followed by bioinformatics and statistical analyses.
Insights Imaging
December 2024
Department of Musculoskeletal Radiology, Fleury Medicina e Saúde Higienópolis, São Paulo, Brazil.
The reported incidence of meniscal tears in the pediatric age group has increased because of increased sports participation and more widespread use of MRI. Meniscal injury is one of the most commonly reported internal derangements in skeletally immature knees and can be associated with early degenerative joint disease leading to disability. The pediatric meniscus has particularities, and knowledge of normal anatomy, anatomical variations, and the patterns of meniscal injury in the pediatric age group is essential to provide a correct diagnosis.
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