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Reduced awareness of cognitive deficits in idiopathic normal pressure hydrocephalus and its change following lumbar puncture.
Cortex
October 2024
Department of Psychology, Bielefeld University, Germany.
Article Synopsis
- The study aimed to explore the relationship between cognitive deficit awareness and executive functions in patients with idiopathic normal pressure hydrocephalus (iNPH), particularly before and after lumbar puncture (LP).
- Researchers compared a group of iNPH patients to participants with other age-related cognitive issues and healthy controls, measuring awareness changes using specific cognitive assessments.
- Results indicated that iNPH patients showed a significant reduction in awareness of cognitive deficits after LP, suggesting that the procedure may help improve their metacognitive abilities.
Osmotic gradients over cell membranes lead to water movement into or out of cells. An intact osmoregulation prevents osmotic gradients, thereby protecting cells from swelling or shrinking. Na is the major cation in the extracellular fluid (ECF) and the major determinant of the osmolarity in the ECF, including plasma.
View Article and Find Full Text PDFPrevention of fetal brain injury in category II tracings.
Acta Obstet Gynecol Scand
December 2023
The Recurrence Prevention Committee, The Japan Obstetric Compensation System for Cerebral Palsy, Japan Council for Quality Health Care, Tokyo, Japan.
Introduction: With category II fetal heart rate tracings, the preferred timing of interventions to prevent fetal hypoxic brain damage while limiting operative interventions remains unclear. We aimed to estimate fetal extracellular base deficit (BD ) during labor with category II tracings to quantify the timing of potential interventions to prevent severe fetal metabolic acidemia.
Material And Methods: A longitudinal study was conducted using the database of the Recurrence Prevention Committee, Japan Obstetric Compensation System for Cerebral Palsy, including infants with severe cerebral palsy born at ≥34 weeks' gestation between 2009 and 2014.
The Effects of Working Memory versus Adaptive Visual Search Control Training on Executive Cognitive Function.
J Cogn Enhanc
September 2022
Department of Psychological Sciences, Purdue University.
There is considerable debate about whether Working Memory (WM) training specifically results in far-transfer improvements in executive cognitive function (ECF) rather than improvements on tasks similar to the training tasks. There has also been recent interest in whether WM training can improve ECF in clinical populations with clear deficits in ECFs. The current study examined the effects of WM training compared with non-WM adaptive Visual Search (VS) control training (15 sessions over 4 weeks) on various measures of ECF, including delay discounting (DD) rate, inhibition on flanker, color and spatial Stroop tasks, and drinking in a community-recruited sample with Alcohol Use Disorder (AUD, 41 men, 41 women, mean age = 21.
View Article and Find Full Text PDFCerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models.
Adv Sci (Weinh)
December 2022
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QU, UK.
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature. This artificially increases the dwelling time of the infected red blood cells within inner organs such as the brain, which can lead to cerebral malaria. Cerebral malaria is the deadliest complication patients infected with P.
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