Endoscope lens with dual fields of view and resolutions for multiphoton imaging.

Opt Lett

School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.

Published: August 2010

AI Article Synopsis

  • A new compact dual-optical-zone endoscope objective lens has been developed, featuring two distinct focus points with numerical apertures of 0.18 and 0.50.
  • The lens enables multiphoton imaging, showcasing the ability to capture images with dual fields of view and differing resolutions.
  • Additionally, the new lens facilitates a combination of both multiphoton and single-photon microscopic imaging techniques.

Article Abstract

We report the development of a miniaturized dual-optical-zone endoscope objective lens. The lens has two foci, with 0.18 and 0.50 NAs. We demonstrate multiphoton imaging with dual fields of view and resolutions using the new lens. A combination of multiphoton and single-photon microscopic imaging is also demonstrated.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038664PMC
http://dx.doi.org/10.1364/OL.35.002735DOI Listing

Publication Analysis

Top Keywords

dual fields
8
fields view
8
view resolutions
8
multiphoton imaging
8
endoscope lens
4
lens dual
4
resolutions multiphoton
4
imaging report
4
report development
4
development miniaturized
4

Similar Publications

Astaxanthin (ASX), "king of carotenoids", is a xanthophyll carotenoid that is characterized by a distinct reddish-orange hue, procured from diverse sources including plants, microalgae, fungi, yeast, and lichens. It exhibits potent antioxidant and anti-ageing properties and has been demonstrated to mitigate ultraviolet-induced cellular and DNA damage, enhance immune system function, and improve cardiovascular diseases. Despite its broad utilization across nutraceutical, cosmetic, aquaculture, and pharmaceutical sectors, the large-scale production and application of ASX are constrained by the limited availability of natural sources, low production yields and stringent production requirements.

View Article and Find Full Text PDF

The (PSS) experiment was part of the European Space Agency's mission and was conducted on the International Space Station from 2014 to 2016. The PSS experiment investigated the properties of montmorillonite clay as a protective shield against degradation of organic compounds that were exposed to elevated levels of ultraviolet (UV) radiation in space. Additionally, we examined the potential for montmorillonite to catalyze UV-induced breakdown of the amino acid alanine and its potential to trap the resulting photochemical byproducts within its interlayers.

View Article and Find Full Text PDF

Seeding Janus Zn-Fe Diatomic Pairs on a Hollow Nanobox for Potent Catalytic Therapy.

Nano Lett

January 2025

Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Material Sciences and Chemical Engineering, Harbin Engineering University, Harbin 150001, P. R. China.

Dual atomic nanozymes (DAzymes) are promising for applications in the field of tumor catalytic therapy. Here, integrating with ultrasmall FeC nanoclusters, asymmetric coordination featuring Janus Zn-Fe dual-atom sites with an ON-Fe-Zn-N moiety embedded in a carbon vacancy-engineered hollow nanobox (Janus ZnFe DAs-FeC) was elaborately developed. Theoretical calculation revealed that the synergistic effects of Zn centers acting as both adsorption and active sites, oxygen-heteroatom doping, carbon vacancy, and FeC nanoclusters jointly downshifted the d-band center of Fe 3d orbitals, optimizing the desorption behaviors of intermediates *OH, thereby significantly promoting catalytic activity.

View Article and Find Full Text PDF

Depression-related innate immune genes and pan-cancer gene analysis and validation.

Front Genet

January 2025

Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, The Key Laboratory of New Drug Pharmacology and Toxicology, Ministry of Education, Collaborative Innovation Center of Hebei Province for Mechanism, Diagnosis and Treatment of Neuropsychiatric Diseases, Hebei Medical University, Shijiazhuang, Hebei, China.

Background: Depression, a prevalent chronic mental disorder, presents complexities and treatment challenges that drive researchers to seek new, precise therapeutic targets. Additionally, the potential connection between depression and cancer has garnered significant attention.

Methods: This study analyzed depression-related gene expression data from the GEO database.

View Article and Find Full Text PDF

Near-Field Mixing in a Coaxial Dual Swirled Injector.

Flow Turbul Combust

November 2024

Institut de Mécanique des Fluides de Toulouse, IMFT, CNRS, Université de Toulouse, Toulouse, France.

Improving mixing between two coaxial swirled jets is a subject of interest for the development of next generations of fuel injectors. This is particularly crucial for hydrogen injectors, where the separate introduction of fuel and oxidizer is preferred to mitigate the risk of flashback. Raman scattering is used to measure the mean compositions and to examine how mixing between fuel and air streams evolves along the axial direction in the near-field of the injector outlet.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!