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Comparison of Double-Blind and Open Food Challenges for the Diagnosis of Food Allergy in Childhood: The ALDORADO Study.
Allergy
December 2024
Department of Pediatrics, Martini Hospital, Groningen, The Netherlands.
Background: Double-blind placebo-controlled food challenge (DBPCFC) is widely regarded as the "gold standard" to diagnose food allergy. Maximum efforts are made to reduce bias, yet DBPCFCs are costly, time-, and resource-intensive. Less demanding open food challenges are increasingly used in clinical practice.
View Article and Find Full Text PDFGenome-Wide Association Study Reveals a Causal Relationship Between Allergic Rhinitis and Hazelnut Allergy.
Allergy
December 2024
Department of Pediatric Pulmonology and Pediatric Allergy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Background: Little is known about the genetics of food allergy (FA) to various allergens and the heterogeneity of FA in adults.
Objective: We aimed to investigate genetic susceptibility to FA in an adult population and to assess the association between secondary FA and allergic rhinitis (AR).
Methods: FA and allergen-specific FA were defined based on in-depth questionnaires and a previously published FA algorithm in the Lifelines.
Upcycling commercial nut byproducts for food, nutraceutical, and pharmaceutical applications: A comprehensive review.
Food Chem
March 2025
Department of Biochemistry, Memorial University of Newfoundland, St. John 's, NL, Canada.
This article presents a comprehensive overview of upcycling commercial nut byproducts (such as Brazil nut, cashew, hazelnut, macadamia, peanut (also known as a legume), pecan, pine nut, pistachio, and walnut) for food, nutraceutical, and pharmaceutical applications. Upcycling nut byproducts, namely husk/hull, hard shell, brown skin, defatted flour/meal/cake, pine cone, cashew nut shell liquid, cashew apple, walnut septum, and dreg/okara, has great potential, not only to reduce/minimise waste, but also to fit within the circular economy concept. Each byproduct has its own unique functional properties, which can bring significant value.
View Article and Find Full Text PDFCharacteristics of wild hazelnut populations in Northeast China and selection of superior provenances.
PLoS One
December 2024
College of Life Sciences, Agriculture and Forestry, Qiqihar University, Qiqihar, China.
Article Synopsis
- China has a diverse range of wild hazelnut resources, yet little research has been done on selecting and domesticating these indigenous strains.
- The study involved eight wild hazelnut populations from seven origins in Heilongjiang Province, which were planted in a provenance trial to assess growth, flowering characteristics, and nut quality.
- Findings showed notable geographical variations in flowering times and pollen characteristics, with the Nehe-originated variegated Corylus heterophylla identified as the best-performing strain based on comprehensive evaluations.
Novel DART-MS approach for rapid and environmentally friendly determination of the geographical origin of hazelnuts (Corylus avellana L.).
Food Chem
March 2025
Hamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany. Electronic address:
Article Synopsis
- DART-MS is an innovative method for verifying the origin of food, offering a viable alternative to traditional techniques.
- This study focused on analyzing 172 hazelnut samples from five different countries to identify unique metabolites using DART-MS and a non-targeted metabolomics approach.
- The results showed a 93.2% accuracy in identifying hazelnut origins, highlighting DART-MS's effectiveness, with the identification of 16 key metabolites, including di- and triacylglycerols, emphasizing their role in food authentication.
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