Purpose: To determine the prevalence and determinants of diabetic retinopathy (DR) in patients ≥18 years at the Cairo University and Sixth of October University hospitals.
Patients And Methods: This is a cross-sectional survey among known diabetic patients attending diabetic clinics. Patients were randomly selected to complete an interviewer-administered questionnaire and a medical assessment. All patients had a dilated fundus examination for evidence of DR using slit-lamp biomicroscopy.
Results: A sample of 1,325 patients was selected with a mean age of 49 years (SD ±12.9). DR was found in 20.5% of patients. Most patients (82%) were not aware of the hazards of diabetes mellitus for the eyes. The prevalence of DR was statistically significantly higher in females (22 vs.17%, p < 0.05), with longer diabetes disease duration (p < 0.001), hypertension (p < 0.001) and absence of hypertension control (p < 0.001), especially proliferative DR. Increasing age and poor glycemic control were associated with a nonsignificant increase in the rate of DR (p = 0.340 and p = 0.444, respectively).
Conclusion: The prevalence of DR in our study population is 20.5%. Regular screening is highly recommended for early detection of DR where timely laser photocoagulation is known to reduce the risk of visual loss in these patients.
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http://dx.doi.org/10.1159/000314876 | DOI Listing |
BMC Endocr Disord
January 2025
Dongzhimen Hospital, Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Objective: To analyze the characteristics of pulmonary nodules (PNs) and related influencing factors in patients with type 2 diabetes mellitus (T2DM).
Methods: Retrospectively analyzed the clinical and biochemical characteristics of 224 patients with PNs and 488 patients with non-PNs in patients with T2DM, and compared the clinical data of 72 patients with large nodules (≥ 5 mm) and 152 patients with small nodules (< 5 mm) in the pulmonary nodules (PNs) group.
Results: Compared to the non-PNs group, the PNs Patients in the group had a longer duration of diabetes, higher age, serum creatinine (SCR), blood urea nitrogen (BUN) and the lower albumin (ALB) and body mass index (BMI); women, diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and estimated glomerular filtration rate (eGFR) < 60 ml/min1.
BMC Ophthalmol
January 2025
Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, China.
Objective: This study aims to investigate the correlation between the development of diabetic retinopathy (DR) and the changes in corneal sub-basal nerve plexus (SNP) and corneal dendritic cells (DCs).
Methods: 58 patients with type 2 diabetes mellitus (T2DM) and 30 age- and sex-matched healthy participants underwent assessment of the corneal nerve. The DR group was divided into no diabetic retinopathy (NDR) and 29 eyes with mild to moderate non-proliferative diabetic retinopathy (NPDR).
Sci Rep
January 2025
Department of Networks and Cybersecurity, Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, Jordan.
Diabetic retinopathy stands as a leading cause of blindness among people. Manual examination of DR images is labor-intensive and prone to error. Existing methods to detect this disease often rely on handcrafted features which limit the adaptability and classification accuracy.
View Article and Find Full Text PDFAm J Ophthalmol
January 2025
Indian Health Outcomes, Public Health, and Economics Research Center, L V Prasad Eye Institute, Hyderabad, Telangana, India; Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India. Electronic address:
Purpose: To evaluate the safety and efficacy of fibrin glue in preventing early recurrence of vitreous haemorrhage following surgery for proliferative diabetic retinopathy (PDR).
Design: Single masked randomized-controlled clinical trial SUBJECTS: Consecutive patients with vitreous haemorrhage due to PDR undergoing primary vitreoretinal surgery were screened. After completing all vitreoretinal manoeuvres including endo-cautery to bleeders, infusion pressure was gradually reduced to 5 mmHg.
Life Sci
January 2025
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Department of Ophthalmology, Friendship Hospital of Ili Kazakh Autonomous Prefecture, Ili, China. Electronic address:
Aims: Diabetic retinopathy (DR) represents one of the most devastating sequences in patients with diabetes. Endothelial dysfunction is a key pathological feature and contributing factor to DR. In the present study we investigated the role of megakaryocytic leukemia 1 (MKL1) in DR pathogenesis.
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