Problem: A high percentage of women schoolteachers having fertility problems were observed by three independent teams.
Method: Expected percentage of educators was calculated in 4650 sub-fertile women and 2,062,891 women at reproductive age. To explore the possibility that schoolteachers' contact with childhood viral infections results in alterations of peripheral blood natural killer (NK) cells, a multiple linear regression analysis for profession, age, difficulty to conceive, number of abortions/implantation failures (predictor variables) was performed in childless educators (210) and housewives (184).
Results: The difference between observed and expected percentage of sub-fertile schoolteachers was statistically significant (17.6% vs 6.86%, P < 0.0001). The mean percentage of PB NK cells was slightly higher in educators compared to housewives (12.48% vs 11.56%, P = 0.10), and the multiple linear regression analysis revealed that the profession (schoolteacher or not) was the only predictive variable for higher NK% values (P = 0.044).
Conclusion: Teachers' sub-fertility appears as an 'occupational disease'. Τhe possibility that results from their exposure to childhood viral infections has to be further explored.
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http://dx.doi.org/10.1111/j.1600-0897.2010.00905.x | DOI Listing |
Hosp Pediatr
December 2024
Department of Pediatrics, Division of Hospital Medicine, The University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.
Background And Objectives: Medical student clinical clerkship evaluations provide feedback for growth and contribute to the clerkship grade and the student's residency application. Their importance is expected to increase even more with the recent change of the US Medical Licensing Examination Step 1 to a pass/fail designation. Timely completion of medical student clerkship evaluations is a problem.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
School of Chemical Engineering, Sichuan University, Chengdu 610065, P. R. China.
To address the issues of infectious virus, bacterial secondary infections, skin pigmentation, and scarring caused by monkeypox virus (MPXV), a sprayable hydrogel with versatile functions was developed with comprehensive properties. Based on current research, the bioactive deep eutectic solvent (DES) of rosmarinic acid-proanthocyanidin-glycol (RPG) was designed and synthesized as active agent, and molecular docking was applied to discover its binding to MPXV proteins through H-bonds and van der Waals interactions, and the docking results show the binding energies between RA, PC, Gly and MPXV proteins are -58.7188, -50.
View Article and Find Full Text PDFTransl Neurodegener
December 2024
Department of Anatomy and Medical Imaging, University of Auckland, 85 Park Road, Grafton, , Auckland, 1142, New Zealand.
Background: Parkinson's disease (PD) and multiple system atrophy (MSA) are classified as α-synucleinopathies and are primarily differentiated by their clinical phenotypes. Delineating these diseases based on their specific α-synuclein (α-Syn) proteoform pathologies is crucial for accurate antemortem biomarker diagnosis. Newly identified α-Syn pathologies in PD raise questions about whether MSA exhibits a similar diversity.
View Article and Find Full Text PDFJ Dairy Sci
January 2025
Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
In a hydrogen-based economy future, hydrogen leakage is becoming an environmental concern. Ruminants naturally produce small amounts of hydrogen, which is emitted in the environment along with other fermentation gases, such as the GHG methane and carbon dioxide. Here, for the first time, we estimated hydrogen emissions from the global ruminant livestock at 527 kt/yr (95% CI: 399, 654), or about 3.
View Article and Find Full Text PDFAm J Vet Res
December 2024
College of Veterinary Medicine, Veterinary Teaching Hospital, Oregon State University, Corvallis, OR.
Objective: To evaluate the precision and accuracy of 3 common methods (method 1, actual draws of the volume remaining; method 2, weight tracking of the volume remaining and/or the volume removed; and method 3, discrepancy percentage at the end of each vial) for monitoring volumes in vials of injectable controlled drugs.
Methods: For methods 1 and 2, doses were drawn from a vial containing a known amount of sterile water. For method 1, after each dose was removed, the remaining quantity of liquid was withdrawn, measured, and reinjected into the vial.
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