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A Neurocysticercosis Case from Timor-Leste, A Previously Unidentified Region of Human Taeniasis Endemicity.
Am J Trop Med Hyg
January 2025
Department of Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul, Republic of Korea.
Neurocysticercosis, a central nervous system infection caused by the zoonotic parasite Taenia solium, is a leading cause of acquired epilepsy worldwide. It is common in areas with extensive pig farming and pork consumption. This report presents an unusual case of neurocysticercosis in a 28-year-old male from Timor-Leste, a region of nonendemicity for human cases of Taenia solium.
View Article and Find Full Text PDFNeuroschistosomiasis in Young Filipino Patient Presenting with Seizure.
Eur J Case Rep Intern Med
October 2024
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
Unlabelled: Neuroschistosomiasis, a rare manifestation of schistosomiasis affecting the central nervous system (CNS), can result in severe neurological complications if not promptly diagnosed and treated. The condition arises due to the development of granulomas around eggs that become lodged within the CNS. Here we present a case report involving a young Filipino individual who had recurrent, uncontrolled seizures, ultimately attributed to neuroschistosomiasis.
View Article and Find Full Text PDFEffectiveness of the Antiparasitic Combination of Albendazole and Praziquantel As Compared With Albendazole Monotherapy in the Treatment of Neurocysticercosis in Children: A Systematic Review and Meta-Analysis.
Cureus
July 2024
Department of Dermatovenereology, Ratna Dewi Principal Clinic, Bekasi, IDN.
Article Synopsis
- * This study investigates whether a combination therapy of albendazole and praziquantel is more effective than albendazole alone in treating pediatric neurocysticercosis, following strict review and analysis protocols.
- * Researchers conducted a systematic review that assessed various randomized controlled trials and quantitatively analyzed the results, utilizing statistical models to compare treatment effectiveness based on lesion resolution in children.
Oxfendazole Nitazoxanide combination in experimental neurocysticercosis - Anti-inflammatory and cysticidal effects.
Exp Parasitol
July 2024
Tropical Pathology and Public Health Institute, Federal University of Goias, Goiânia, Goiás, CEP: 74605-050, Brazil. Electronic address:
Neurocysticercosis (NCC) is a parasitic infection caused by the larval stage of the pork tapeworm, Taenia solium. The complications of NCC include seizures, headaches, cognitive impairment, and focal neurological deficits. In addition to antiparasitic drugs and surgery, the management of NCC includes the use of corticosteroids to reduce inflammation and control symptoms.
View Article and Find Full Text PDFUnderstanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis.
Brain Pathol
September 2024
Infectious Diseases Laboratory Research-LID, Facultad de Ciencia e Ingeniería, Universidad Peruana Cayetano Heredia, Lima, Peru.
Despite being a leading cause of acquired seizures in endemic regions, the pathological mechanisms of neurocysticercosis are still poorly understood. This study aims to investigate the impact of anthelmintic treatment on neuropathological features in a rat model of neurocysticercosis. Rats were intracranially infected with Taenia solium oncospheres and treated with albendazole + praziquantel (ABZ), oxfendazole + praziquantel (OXF), or untreated placebo (UT) for 7 days.
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