The type-III interferons (IFNs) are the most recently discovered IFNs in the human immune system and have important, but as yet poorly characterized, functions in innate and adaptive immunity that complement their antiviral functions. It is now becoming clear that these type-III IFNs have a functional niche where epithelial surfaces interact with the adaptive immune system, that their antiviral capability is not as highly developed as that of the type-I IFNs, and that they have their own profile of immunomodulatory functions; specifically, they are key modulators of the T-helper (Th)2 response.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/jir.2010.0081 | DOI Listing |
Publication Analysis
Top Keywords
immune system
8
lambda interferons
4
interferons guardians
4
guardians immune-epithelial
4
immune-epithelial interface
4
interface t-helper
4
t-helper response
4
response type-iii
4
type-iii interferons
4
ifns
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!