Decompressive craniectomy for acute disseminated encephalomyelitis.

Neurocrit Care

Division of Clinical Neurosciences, University of Southampton, LD83, Level D, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

Published: December 2010

AI Article Synopsis

  • Acute disseminated encephalomyelitis (ADEM) is a rare condition that can cause severe brain swelling and rapid neurological decline.
  • A case study shows a patient with a hyperacute onset who experienced quick loss of consciousness and neurological deficits; emergency surgery and steroids were used to treat the patient.
  • The results support that swift surgical decompression is crucial in severe ADEM cases, leading to significant recovery and minimal long-term effects.

Article Abstract

Background: Acute disseminated encephalomyelitis (ADEM) is a rare, acute demyelinating condition. Although it usually presents in an acute or subacute manner over days, its clinical course may be rapid with symptoms and signs of severe intracerebral mass effect secondary to cerebral oedema.

Methods: Case report and literature review.

Results: We report a case of a patient presenting with a hyperacute course manifested by rapid loss of consciousness and focal neurological signs. Management with emergency hemicraniectomy and steroids resulted in rapid neurological improvement and minimal long-term deficit.

Conclusions: We believe that only surgical decompression is likely to be life saving in similar cases of hyperacute cerebral oedema due to ADEM. The wide decompression performed was concordant with that indicated for traumatic brain swelling. Such aggressive management is vindicated by the rapid recovery shown by our patient within days of surgery and the finding of minimal neurological sequelae at 3 months.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12028-010-9420-8DOI Listing

Publication Analysis

Top Keywords

acute disseminated
8
disseminated encephalomyelitis
8
decompressive craniectomy
4
acute
4
craniectomy acute
4
encephalomyelitis background
4
background acute
4
encephalomyelitis adem
4
adem rare
4
rare acute
4

Similar Publications

Background: Many children and adolescents with cerebral palsy (CP) experience cognitive difficulties, impacting their academic, social, and emotional well-being. A Danish study from 2023 revealed that merely 40% of individuals with CP complete their elementary school education, and previous neuropsychological studies have found that most children and adolescents with CP experience cognitive difficulties. Yet, cognitive functioning is often assumed rather than assessed, and CP follow-up programs focus predominantly on physical functioning.

View Article and Find Full Text PDF

Introduction: Tobacco smoking remains a leading cause of ill-health, premature mortality and a driver of health inequalities. To support smokers in England, a comprehensive approach to treating tobacco dependence is being implemented. This includes offering support to all people admitted to hospitals, as well as women and pregnant people within NHS settings.

View Article and Find Full Text PDF

Background: The complexity of acute myeloid leukemia (AML) is increasingly recognized through the identification of distinct subgroups, including those with an APL-like immunophenotype characterized by the absence of CD34 and HLA-DR expression, which is widely recognized as a representative immunophenotype in acute promyelocytic leukemia (APL). This study sought to understand the clinical, molecular, and prognostic differences between AML patients with and without this phenotype.

Methods: This study retrospectively analysed 191 de novo non-M3 AML patients and identified 32 patients with the CD34HLA-DR phenotype resembling APL-like immunophenotype, considered as the experimental group.

View Article and Find Full Text PDF

Emergence of Omicron FN.1 a descendent of BQ.1.1 in Botswana.

Virus Evol

November 2024

Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.

Botswana, like the rest of the world, has been significantly impacted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In December 2022, we detected a monophyletic cluster of genomes comprising a sublineage of the Omicron variant of concern (VOC) designated as B.1.

View Article and Find Full Text PDF

Background: is one of the major pathogens in mucormycosis. Infection due to is rare and has a high mortality rate, especially disseminated mucormycosis infections. Rapid and accurate pathogen identification is important for the development of targeted antifungal therapies.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!