We used structural equation modeling to test the hypothesis that a General Factor of Personality (GFP) occupies the apex of the hierarchy of personality disorders in three validation samples of the Dimensional Assessment of Personality Pathology - Basic Questionnaire (DAPP-BQ). In a general population sample (N = 942), we found a GFP explained 34% of the variance in four first-order factors and 33% of the variance in all 18 scales. In a twin sample (N = 1,346), a GFP explained 35% of the variance in four first-order factors and 34% of the variance in all 18 scales. In a clinical sample (N = 656), a GFP explained 34% of the variance in four first-order factors and 30% of the variance in all 18 scales.
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http://dx.doi.org/10.1375/twin.13.4.301 | DOI Listing |
Aging Cell
December 2024
Department of Developmental Biology, Washington University in St. Louis, St. Louis, Missouri, USA.
Biophys J
November 2024
Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Delft, the Netherlands. Electronic address:
Methods Mol Biol
November 2024
Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Unlabelled: The capsular polysaccharide synthesis ( ) locus of is implicated in invasive meningococcal disease. The synthesis ( ) and transport ( ) operons are transcribed in opposite directions from a common intergenic region and expression is negatively regulated by the bacterial two-component system and thermosensitive RNA folding. However, these mechanisms do not fully explain the stationary phase responses and the cis-acting elements remain to be fully characterized.
View Article and Find Full Text PDFbioRxiv
October 2024
Intercollege Program in Integrative and Biomedical Physiology, Pennsylvania State University, University Park, PA 16802.
Intracellular vesicles are typically transported by a small number of kinesin and dynein motors. However, the slow microtubule binding rate of kinesin-1 observed in biophysical studies suggests that long-range transport may require a high number of motors. To address the discrepancy in motor requirements between and studies, we reconstituted motility of 120-nm-diameter liposomes driven by multiple GFP-labeled kinesin-1 motors.
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