Estimation of the postmortem interval (PMI) is a practical task in daily forensic casework. Researches on PMI is an important practical project in forensic field. Estimation of the time since death is influenced by internal and external, antemortem and postmortem factors, thus the old methods have limitations. Fourier transform infrared (FTIR) spectroscopy has been applied to study the pure protein, nucleic acid and carbohydrate and to detect the changes in complex cells and tissues. At present because the powerful software has could be used to achieve the spectrum transformation, smoothing, baseline correction and normalization, it is possible to analyze the samples quantitatively with the FTIR which has been applied in the biology and clinical medicine. This paper has reviewed the mechanism of FTIR and its application in biomedicine. The postmortem FTIR spectral changes were also discussed, which showed its potential for estimating PMI.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Radiocarbon and bomb pulse dating in the forensic context: A systematic review.
Forensic Sci Int
January 2025
Forensic Medicine, Forensic Science and Sports Medicine Section, Department of Medicine and Surgery, University of Perugia, Piazza Lucio Severi, Perugia, Italy. Electronic address:
Radiocarbon analysis in bones, particularly through Bomb Pulse dating, is an essential tool in forensic investigations for estimating the postmortem interval of human remains. However, there are some limitations related to the interpretation of laboratory data, since this can differ from the Post Mortem Interval by many years, depending on the anatomical district and the bone part sampled, as well as the age of the individual and other parameters, since these elements influence bone turnover. In recent years, many studies have been conducted, but with non-standardized data and on limited samples.
View Article and Find Full Text PDFEffect of fluctuating temperatures on the development of forensically important fly species, Chrysomya megacephala (Diptera: Calliphoridae).
Forensic Sci Int
January 2025
Department of Forensic Medicine, Soochow University, Ganjiang East Road, Suzhou, Jiangsu, China. Electronic address:
Necrophagous blow flies are a commonly used forensic tool to estimate the minimum postmortem interval (PMI), where researchers collect development data under constant temperature regimes and construct models to estimate PMI. However, the ambient temperatures of real death scenes are often fluctuant, which limits the reliability of data obtained under constant temperature regimes. Here we investigate the possible differences in the development of Chrysomya megacephala (Fabricius, 1794) (Diptera: Calliphoridae), an important species in forensic entomology.
View Article and Find Full Text PDFLongitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum.
JAMA Neurol
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota.
Importance: Although 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a well-established cross-sectional biomarker of brain metabolism in dementia with Lewy bodies (DLB), the longitudinal change in FDG-PET has not been characterized.
Objective: To investigate longitudinal FDG-PET in prodromal DLB and DLB, including a subsample with autopsy data, and report estimated sample sizes for a hypothetical clinical trial in DLB.
Design, Setting, And Participants: Longitudinal case-control study with mean (SD) follow-up of 3.
Cooking loss estimation of semispinalis capitis muscle of pork butt using a deep neural network on hyperspectral data.
Meat Sci
January 2025
Department of Biosystems Machinery Engineering, Chungnam National University, Daejeon 34134, Republic of Korea. Electronic address:
This study evaluated the performance of a deep-learning-based model that predicted cooking loss in the semispinalis capitis (SC) muscle of pork butts using hyperspectral images captured 24 h postmortem. To overcome low-scale samples, 70 pork butts were used with pixel-based data augmentation. Principal component regression (PCR) and partial least squares regression (PLSR) models for predicting cooking loss in SC muscle showed higher R values with multiplicative signal correction, while the first derivative resulted in a lower root mean square error (RMSE).
View Article and Find Full Text PDFContinuous increase in podocyte numbers in the first 36 months of life-insights from forensic autopsies in Japanese children.
Pediatr Nephrol
January 2025
Department of Pediatrics, Shiga University of Medical Science, Shiga, 520-2192, Japan.
Background: Podocyte depletion is a critical factor in glomerulosclerosis development. While podocyte numbers per glomerulus typically decline with age in adults, they are hypothesized to increase during childhood. However, studies on podocyte number progression in childhood have been limited.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!